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Sigma-Aldrich

Gold nanoparticles

40 nm diameter, OD 1, stabilized suspension in 0.1 mM PBS, reactant free

Synonym(s):

Au NP, Gold colloid

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About This Item

MDL number:
MFCD00003436
UNSPSC Code:
12352302
PubChem Substance ID:
329766383
NACRES:
NA.23
Pricing and availability is not currently available.

form

nanoparticles
suspension

concentration

~7.2E+10 particles/mL

OD

1

diameter

40 nm

λmax

526-531 nm

storage temp.

2-8°C

SMILES string

[Au]

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Gold nanoparticles (AuNPs), 40 nm are quasi dynamic colloidal nanomaterials with good surface chemistry and high surface to volume ratio. Their properties include high stability, biocompatibility, and low toxicity which make them useful in biological applications.[1][2][3][4][5][6]

Application

AuNPs can be used for a variety of applications such as biomedical, electrochemical and energy based devices. They can also be used in drug delivery and biosensing based device fabrication. [1][2][3][4][5][6][7]

Legal Information

Product of CytoDiagnostics, Inc.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV4747
MKCV2727
MKCT1076
MKCT7416
MKCQ7761

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Gold Nanoparticles For Physics, Chemistry And Biology (Second Edition) (2012)
Guy Nir et al.
PLoS genetics, 14(12), e1007872-e1007872 (2018-12-27)
Chromosome organization is crucial for genome function. Here, we present a method for visualizing chromosomal DNA at super-resolution and then integrating Hi-C data to produce three-dimensional models of chromosome organization. Using the super-resolution microscopy methods of OligoSTORM and OligoDNA-PAINT, we
Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements
Her S, et al.
Advanced Drug Delivery Reviews, 109(6), 84-101 (2017)
Gold nanoparticles for applications in energy and environment: synthesis and characterization
Chen Y
Rare Metals, 30(1), 116-120 (2011)
Spectroscopic Study of the Interaction of Carboxyl-Modified Gold Nanoparticles with Liposomes of Different Chain Lengths and Controlled Drug Release by Layer-by-Layer Technology
Kanwa N, et al.
The Journal of Physical Chemistry B, 121(50), 11333-11343 (2017)
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Articles

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

Surface-enhanced Solar Energy Conversion Systems

Sustainable energy sources with high production efficiency are crucial for meeting increasing energy demand.

Sensitivity Lateral Flow Diagnostic Assays

Steven J. Oldenburg, Ph.D. provides an overview of lateral flow diagnostic assays and discusses the use of ultra-bright reporter particles based on the unique optical properties of gold nanoshells that significantly increase the sensitivity of lateral flow immunoassays.

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Questions

1–10 of 13 Questions  

  1. Are this gold nanoparticles citrate-stabilized?

    1 answer

    1. This product is citrate stabilized gold colloid in 0.1 mM PBS.

      Helpful?

  2. which size of particule is recommended for SERS?

    1 answer

    1. We do not have a specific particle size of Gold Nanoparticle (AuNP) that is recommended for Surface-Enhanced Raman Spectroscopy. It is recommended to refer to the chemical literature to see what other researchers have used for this application.

      To further discuss, we kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquires" under the Products Section with all the required information so that a member of our team can reach out to you to assist further. Thank you.

      Helpful?

  3. How do you attach gold nanoparticles to peptides and peptide conjugates?

    1 answer

    1. To view information on how to attach gold nanoparticles to peptides and peptide conjugates, please view the information in the reference - Rosenthal, S. J. and Wright, D. W. (Eds.). (2005), p. 91-92. NanoBiotechnology Protocols. New Jersey. Humana Press.

      Helpful?

  4. How do you attach gold nanoparticles to oligos?

    1 answer

    1. To attach gold nanoparticles to oligos please view the information in the attached reference - Bioconjug Chem. 2011 Apr 20;22(4):794-807. Epub 2011 Mar 28.

      Helpful?

  5. Which gold nanoparticle size should I choose for my application?

    1 answer

    1. The size of gold nanoparticle to use is very depandent upon the intended application. Generally, smaller particles offer better sensitivity in applications such as immunogold labeling due to less steric hindrance and the ability to bind more gold nanoparticles to the desired target. Small gold nanoparticles are less visible than larger particles, however, which must also be taken into account.As an application example, particles with a size between 30-50nm are particularly useful for the development of rapid tests such as lateral flow assays.

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  6. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. Can the Gold nanoparticles be frozen?

    1 answer

    1. No, the Gold nanoparticles should not be frozen.  If frozen, the gold nanoparticles will irreversibly aggregate, turning the solution clear.

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  8. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  9. How do you attach gold nanoparticles to glass?

    1 answer

    1. To view the procedure on how to attach gold nanoparticles to glass please view information in the reference - Journal of Atomic, Molecular, and Optical PhysicsVolume 2012 (2012). Article ID 683830, 6 pagesdoi:10.1155/2012/683830

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  10. Do I need to wash my gold nanoparticles?

    1 answer

    1. For most applications, our gold nanoparticles can be used without any additional washing steps. If you have a sensitive application that requires additional washing the best way to do so is by either centrifugation or filtration.

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1–10 of 13 Questions  

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