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Key Documents

M6385

Sigma-Aldrich

Methyl cellulose

viscosity: 25 cP

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

Quality Level

form

powder

color

white to off-white

viscosity

20-30 cP, 2 % in water(20 °C)

SMILES string

[*]OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO[*])O[C@@H](O[*])[C@H](O[*])[C@H]2O[*])[C@H](O[*])[C@@H](O[*])[C@@H]1O[*]

InChI key

YLGXILFCIXHCMC-JHGZEJCSSA-N

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General description

Methyl cellulose (MC) is a simple derivative of cellulose.

Application

Methyl cellulose has been used:
  • as a supplement for culturing multicellular spheroids of SH-SY5Y cells
  • as a supplement for culturing tumor cell spheroids
  • to generate and study the rheological behavior of aqueous mullite-albumin-methylcellulose systems

Biochem/physiol Actions

Methyl cellulose (MC) acts as a laxative and is hydrophilic. It has therapeutic effects against constipation, irritable bowel syndrome, and diverticulosis due to its bulk-forming and stool softening properties. MC has the potential to treat patients with ileostomies and colostomies. It may also be used as a stabilizer and emulsifier. MC is a component of eye drops and contact lens solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rheological behavior of aqueous mullite-albumin-methylcellulose systems
Sandoval M, et al.
Ceramics International, 43(9) (2017)
Methylcellulose
Kieth H.
xPharm: The Comprehensive Pharmacology Reference, 1-3 (2007)
Methylcellulose, a cellulose derivative with original physical properties and extended applications
Nasatto P L, et al.
Polymers, 7(5), 777-803 (2015)
Eyedrops and ointments
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 220-221 (2016)
Timo Z Nazari-Shafti et al.
Biomolecules, 10(9) (2020-09-26)
The cardioprotective properties of extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) are currently being investigated in preclinical studies. Although microRNAs (miRNAs) encapsulated in EVs have been identified as one component responsible for the cardioprotective effect of MSCs, their

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