Skip to Content
Merck
All Photos(1)

Key Documents

80424

Sigma-Aldrich

Di(N-succinimidyl) glutarate

≥97.0% (CHN)

Synonym(s):

DSG

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C13H14N2O8
CAS Number:
Molecular Weight:
326.26
Beilstein:
8575145
MDL number:
UNSPSC Code:
12161502
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥97.0% (CHN)

form

lumps

reaction suitability

reagent type: cross-linking reagent

storage temp.

−20°C

SMILES string

O=C(CCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C13H14N2O8/c16-8-4-5-9(17)14(8)22-12(20)2-1-3-13(21)23-15-10(18)6-7-11(15)19/h1-7H2

InChI key

LNQHREYHFRFJAU-UHFFFAOYSA-N

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Homobifunctional cross-linking reagent; e.g. isolation of insulin receptor

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nikki Minnebo et al.
Nucleic acids research, 41(2), 842-854 (2012-12-18)
The histone methyltransferase EZH2 regulates cell proliferation and differentiation by silencing Polycomb group target genes. NIPP1, a nuclear regulator of serine/threonine protein phosphatase 1 (PP1), has been implicated in the regulation of EZH2 occupancy at target loci, but the underlying
Anetta Ptasinska et al.
Cell reports, 28(12), 3022-3031 (2019-09-19)
Acute myeloid leukemia (AML) is associated with mutations in transcriptional and epigenetic regulator genes impairing myeloid differentiation. The t(8;21)(q22;q22) translocation generates the RUNX1-ETO fusion protein, which interferes with the hematopoietic master regulator RUNX1. We previously showed that the maintenance of
Yong-Jie Zhang et al.
Human molecular genetics, 22(15), 3112-3122 (2013-04-12)
TAR DNA-binding protein-43 (TDP-43) is the principal component of ubiquitinated inclusions in amyotrophic lateral sclerosis (ALS) and the most common pathological subtype of frontotemporal dementia-frontotemporal lobar degeneration with TDP-43-positive inclusions (FTLD-TDP). To date, the C-terminus of TDP-43, which is aggregation-prone
Margaret Johnson et al.
Journal of acquired immune deficiency syndromes (1999), 81(4), 463-472 (2019-04-16)
Doravirine is a novel, nonnucleoside reverse transcriptase inhibitor with demonstrated efficacy in treatment-naive adults with HIV-1. In this open-label, active-controlled, noninferiority trial, adults with HIV-1 virologically suppressed for ≥6 months on 2 nucleoside reverse transcriptase inhibitors plus a boosted protease
S M Waugh et al.
Biochemistry, 28(8), 3448-3455 (1989-04-18)
Radiolabeled insulin was affinity cross-linked to purified insulin receptor with six separate bifunctional N-hydroxysuccinimide esters of different lengths. Results were qualitatively identical for each cross-linker in that insulin was predominantly cross-linked through its B chain to the receptor's alpha subunit.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service