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Sigma-Aldrich

(±)-Pinostrobin

≥99.0% (TLC)

Synonym(s):

(RS)-2,3-Dihydro-5-hydroxy-7-methoxy-2-phenyl-4H-1-benzopyran-4-one

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About This Item

Empirical Formula (Hill Notation):
C16H14O4
CAS Number:
Molecular Weight:
270.28
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥99.0% (TLC)

SMILES string

COc1cc(O)c2C(=O)CC(Oc2c1)c3ccccc3

InChI

1S/C16H14O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-8,14,17H,9H2,1H3

InChI key

ORJDDOBAOGKRJV-UHFFFAOYSA-N

Application

(±)-Pinostrobin, a chiral flavonoid (±), may be used in the development of analytical methods for separation of its individual enantiomers. Pinostrobin may be used to study its neuroprotective antioxidant effects.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yan-Fang Xian et al.
Cellular and molecular neurobiology, 32(8), 1223-1230 (2012-05-09)
Beta-Amyloid peptide (Aβ), a major protein component of brain senile plaques in Alzheimer's disease (AD), has been considered as a critical cause in the pathogenesis of AD. Pinostrobin, a potent flavonoid inducer, is the major and most active ingredient of
Monika Asztemborska et al.
Electrophoresis, 24(15), 2527-2531 (2003-08-06)
Micellar electrokinetic chromatography (MEKC) was applied for enantioseparation of selected flavanones, including naringin, hesperidin, neohesperidin, naringenin, hesperetin, pinostrobin, isosakuranetin, eriodictyol, and homoeriodictyol. gamma-Cyclodextrin (gamma-CD) and sodium cholate (SCh) were used as chiral modifiers inducing enantioselectivity to the background electrolyte. From
Alka Jaudan et al.
PloS one, 13(2), e0191523-e0191523 (2018-02-09)
Pinostrobin (PN) is a naturally occurring dietary bioflavonoid, found in various medicinal herbs/plants. Though anti-cancer potential of many such similar constituents has been demonstrated, critical biochemical targets and exact mechanism for their apoptosis-inducing actions have not been fully elucidated. The
Stereospecific analytical method development and preliminary in vivo pharmacokinetic characterization of pinostrobin in the rat.
Sayre CL, Zhang Y, Martinez SE, et al.
Biomedical Chromatography (2012)
Karen J Marsh et al.
Phytochemistry, 160, 31-39 (2019-01-27)
A group of plant specialised metabolites (PSMs) collectively known as unsubstituted B-ring flavanones (UBFs) have previously been found in the foliage of some species from the genus Eucalyptus L'Hér. (Myrtaceae), specifically from the subgenus Eucalyptus (monocalypts). Captive feeding studies using

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