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Protease Inhibitor Cocktail IV

liquid, for the inhibition of serine proteases, cysteine proteases, aspartic proteases and metalloproteases. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Synonym(s):

Protease inhibitor cocktail

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.54

product name

Protease Inhibitor Cocktail Set IV, The Protease Inhibitor Cocktail Set IV controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

shipped in

wet ice

storage temp.

−20°C

General description

A cocktail of four protease inhibitors with broad specificity for the inhibition of aspartic-, cysteine-, metallo-, and serine-proteases. Recommended for fungal and yeast cell extracts. Each vial contains 100 mM AEBSF, HCl (Cat. No. 101500), 1.5 mM E-64 (Cat. No. 324890), 2 mM Pepstatin A (Cat. No. 516481), and 500 mM 1,10-Phenanthroline (Cat. No. 516705). Supplied with a data sheet. Note: 1 set = 5 x 1 ml.
The Protease Inhibitor Cocktail Set IV controls the activity of Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Specificity

Inhibits a broad spectrum of serine proteases, cysteine proteases, aspartic proteases, and metalloproteases.

Application

Protease Inhibitor Cocktail Set IV, is a cocktail of four protease inhibitors with broad specificity for the aspartic, cysteine, metallo & serine-proteases. Recommended for fungal & yeast cells.

Biochem/physiol Actions

Primary Target
aspartic-, cysteine-, metallo-, and serine-proteases
Product does not compete with ATP.

Warning

Toxicity: Toxic (F)

Physical form

In 1 ml DMSO.

Reconstitution

Protease Inhibitor Cocktail Set IV can be used at a 1:100-1:1000 dilution for most applications.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

188.6 °F - Information refers to the main ingredient.

Flash Point(C)

87 °C - Information refers to the main ingredient.


Certificates of Analysis (COA)

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Joseph V Geisberg et al.
Current protocols in molecular biology, 128(1), e101-e101 (2019-09-11)
Here we describe CLIP-READS, a technique that combines elements of crosslinking and immunoprecipitation (CLIP) and 3' region extraction and deep sequencing (READS), to provide a genome-wide map of mRNA 3' isoform binding by a given messenger ribonucleoprotein (mRNP). In CLIP-READS
Chaperones directly and efficiently disperse stress-triggered biomolecular condensates.
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Haneul Yoo et al.
STAR protocols, 3(2), 101409-101409 (2022-05-24)
Heat stress triggers a specific set of proteins in budding yeast to form solid-like biomolecular condensates, which are dispersed by molecular chaperones. Here, we describe a protocol to study the kinetics of chaperone-facilitated condensate dispersal using biochemical reconstitution and fluorescence anisotropy.
Micaela Boiero Sanders et al.
The EMBO journal, 41(5), e107982-e107982 (2022-02-19)
A paradox of eukaryotic cells is that while some species assemble a complex actin cytoskeleton from a single ortholog, other species utilize a greater diversity of actin isoforms. The physiological consequences of using different actin isoforms, and the molecular mechanisms
Zhouying Wu et al.
Frontiers in molecular biosciences, 8, 707295-707295 (2021-09-14)
The inhibitor of CDK4/6 has been clinically used for treating certain types of cancer which are characterized by G0/G1 acceleration induced by the CDK4/6-RB1 pathway. On the contrary, the cell cycle-related molecules are abnormal in over 50% of the patients

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