233490

Coagulation Factor XII, Human Plasma

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.

• Synonym(s): Coagulation Factor XII, Human Plasma
• CAS Number: 9001-30-3
• UNSPSC Code: 12352202
• NACRES: NA.42

Properties

• Quality Level: 100
• form: liquid
• specific activity: ≥20 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• shipped in: wet ice
• storage temp.: −70°C

Description

General description

Coagulation Factor XII, Human Plasma, CAS 9001-30-3, is a native coagulation factor XI that once activated (principally by kallikrein), is converted to Factor α-XIIa.

Native coagulation factor XII from human plasma. A single-chain polypeptide which, once activated (principally from the action of kallikrein), is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.

Native coagulation factor XII from human plasma. A single-chain polypeptide, which once activated (principally from the action of kallikrein) is converted to Factor α-XIIa. Factor α-XIIa then converts Factor XI to Factor XIa.

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Unit Definition

Specific activity is measured by clotting assay and compared to a standard curve produced using normal pooled human plasma.

Physical form

In 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

single band by SDS-PAGE

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Flash Point(F): Not applicable
• Flash Point(C): Not applicable