Skip to Content
Merck
All Photos(1)

Key Documents

73340

Sigma-Aldrich

5-Nitro-2-furaldehyde semicarbazone

≥97.0% (HPLC)

Synonym(s):

5-Nitro-2-furfural semicarbazone, Furacin, NFZ, Nitrofurazone

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C6H6N4O4
CAS Number:
Molecular Weight:
198.14
Beilstein:
86403
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥97.0% (HPLC)

form

powder

mp

242-244 °C (lit.)

SMILES string

NC(=O)N\N=C\c1ccc(o1)[N+]([O-])=O

InChI

1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+

InChI key

IAIWVQXQOWNYOU-FPYGCLRLSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Molecules of 5-nitro-2-furaldehyde semicarbazone are linked via bifurcated hydrogen bonds. Its crystal structure has been studied. It is reported to induce mammary fibroadenomas in Holtzman female rats and can be subcutaneously transplanted into male and female newborn Holtzman rats. Chemotheraupetic potential of 5-nitro-2-furaldehyde semicarbazone has been evaluated. 5-Nitro-2-furaldehyde semicarbazone is a synthetic nitrofuran derivative, having good bacteriostatic and bactericidal properties, with an antibacterial action against a number of gram-negative and gram-positive microorganisms. In Vitro toxicity of 5-nitro-2-furaldehyde semicarbazone has been investigated in hamster cells.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Muta. 2 - Repr. 2 - Skin Sens. 1 - STOT RE 2

Target Organs

male reproductive organs

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nitrofurans as radiosensitizers of hypoxic mammalian cells.
J D Chapman et al.
Cancer research, 32(12), 2616-2624 (1972-12-01)
Sonoelectrodeposition of gold nanorods at a gold surface-Application for electrocatalytic reduction and determination of nitrofurazone.
Rahi A, et al.
Sensors and Actuators B, Chemical (2014)
The chemotherapeutic properties of 5-nitro-2-furaldehyde semicarbazone (furacin).
M C DODD
The Journal of pharmacology and experimental therapeutics, 86, 311-323 (1946-04-01)
Transplantable rat mammary tumors induced by 5-nitro-2-furaldehyde semicarbazone and by formic acid 2-[4-(5-nitro-2-furyl)-2-thiazolyl] hydrazide.
E Ertürk et al.
Cancer research, 30(5), 1409-1412 (1970-05-01)
5-Nitro-2-furaldehyde semicarbazone.
Olszak TA, et al.
Acta Crystallographica Section C, Structural Chemistry, 50(6), 948-950 (1994)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service