155195
N,O-Bis(trimethylsilyl)trifluoroacetamide
≥99%
Synonym(s):
BSTFA
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About This Item
Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
Molecular Weight:
257.40
Beilstein:
2050024
EC Number:
MDL number:
UNSPSC Code:
12352111
PubChem Substance ID:
NACRES:
NA.22
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grade
synthesis grade
Assay
≥99%
form
liquid
refractive index
n20/D 1.384 (lit.)
bp
45-50 °C/14 mmHg (lit.)
density
0.969 g/mL at 25 °C (lit.)
functional group
fluoro
SMILES string
C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F
InChI
1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+
InChI key
XCOBLONWWXQEBS-KPKJPENVSA-N
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General description
N,O-Bis(trimethylsilyl)trifluoroacetamide is an organosilicon reagent for trimethylsilylation, deprotection, dehydrogenation, allylic alkylation, nitronate formation, and Claisen rearrangement.
BSTFA is a silylating agent used in the synthesis of 4-Quinolones.[1]
BSTFA is a silylating agent used in the synthesis of 4-Quinolones.[1]
Application
N,O-Bis(trimethylsilyl)trifluoroacetamide can be used as a derivatization reagent for the determination of the estrogens estrone and 17α-ethinylestradiol by gas chromatography-mass spectrometry.
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Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
93.2 °F
Flash Point(C)
34 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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