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M4696

Sigma-Aldrich

Anti-Matrix Metalloproteinase-1 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym(s):

Anti-MMP-1

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About This Item

MDL number:
MFCD01321860
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 2-15 μg/mL
western blot: 0.1-0.2 μg/mL

UniProt accession no.

P03956

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP1(4312)

Specificity

The antibody reacts with reduced and non-reduced MMP-1 and recognizes the proform and active forms of MMP-1.

Immunogen

purified, CHO cell-derived, recombinant human MMP-1 (interstitial collagenase).

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Corinne Granger et al.
Dermatology and therapy, 10(6), 1315-1329 (2020-09-12)
Extrinsic factors, such as solar radiation and urban pollution, cause damage that alters the structure, function and appearance of skin. The aim of this study was to determine the ability of a night cream containing melatonin, carnosine and Helichrysum italicum extract
Magnus S Ågren et al.
European journal of cell biology, 94(1), 12-21 (2014-12-03)
Tumor necrosis factor (TNF)-α induces matrix metalloproteinases (MMPs) that may disrupt skin integrity. We have investigated the effects and mechanisms of exogenous TNF-α on collagen degradation by incubating human skin explants in defined serum-free media with or without TNF-α (10ng/ml)

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