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Sigma-Aldrich

L-Leucinamide hydrochloride

99%

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About This Item

Linear Formula:
(CH3)2CHCH2CH(NH2)CONH2·HCl
CAS Number:
Molecular Weight:
166.65
Beilstein:
4237021
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

optical activity

[α]25/D +10°, c = 5 in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

254-256 °C (lit.)

application(s)

peptide synthesis

SMILES string

Cl.CC(C)C[C@H](N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H/t5-;/m0./s1

InChI key

VSPSRRBIXFUMOU-JEDNCBNOSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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P Clapés et al.
Journal of biotechnology, 15(4), 323-338 (1990-09-01)
Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in
Tsonko Kolev et al.
Amino acids, 37(4), 693-701 (2008-10-28)
The hydrogensquarate [LeuNH(2)] (HSq) of L-leucinamide has been synthesized and its structure has been determined by single crystal X-ray diffraction. A three dimensional network is formed by hydrogen bonds with participation of the O=C-NH(2) function, the hydrogensquarate ion and the
J C Hafkenscheid et al.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 23(7), 393-398 (1985-07-01)
A continuous procedure for the determination of leucine aminopeptidase is described. L-leucinamide is used as substrate and the liberated ammonia is determined with the glutamate dehydrogenase reaction. The enzyme is Mn2+-activated and 30 mumol/l MnCl2 is necessary for an optimal
Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide.
H Spahn
Journal of chromatography, 423, 334-339 (1987-12-25)
[Marked dissociation of leucine aminopeptidase activities by the use of 2 different substrates--application of the methods to lymphatic diseases].
Y Hirasawa et al.
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 45(5), 907-912 (1982-09-01)

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