W1895

WAY-100135

≥98% (HPLC)

• Synonym(s): 3-[4-(2-Methoxyphenyl)piperazin-1-yl]-2-phenyl-N-tert-butyl-propanamide dihydrochloride;, N-tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl) -2-phenylpropanamide dihydrochloride
• Empirical Formula (Hill Notation): C₂₄H₃₃N₃O₂ · 2HCl
• CAS Number: 149055-79-8
• Molecular Weight: 468.46
• NACRES: NA.77
• PubChem Substance ID: 329830428
• UNSPSC Code: 12352200
• MDL number: MFCD00903910
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: H₂O: ≥10 mg/mL
• originator: Wyeth
• storage temp.: 2-8°C
• SMILES string: Cl.Cl.COc1ccccc1N2CCN(CC2)CC(C(=O)NC(C)(C)C)c3ccccc3
• InChI: 1S/C24H33N3O2.2ClH/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4;;/h5-13,20H,14-18H2,1-4H3,(H,25,28);2*1H
• InChI key: VJGZNBYDSDEOED-UHFFFAOYSA-N

Description

Biochem/physiol Actions

WAY-100135 is a potent, selective 5-HT_1A receptor antagonist (IC50 = 15 nM). It is selective over 5-HT_{1B, 1C, 2},α1, α2 and D₂ receptors (IC50 > 1000 nM).

WAY-100135 is a potent, selective 5-HT_1A receptor antagonist (IC50 = 15 nM). Selective over 5-HT_1B,1C,2, α1, α2 and D₂ receptors (IC50 > 1000 nM).

Features and Benefits

This compound was developed by Wyeth. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable