TRUERGD
TrueGel3D RGD
Integrin Adhesion Peptide
Synonym(s):
3D cell culture matrix
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About This Item
NACRES:
NA.71
UNSPSC Code:
12352207
Pricing and availability is not currently available.
shipped in
dry ice
storage temp.
−20°C
General description
TrueGel3D® is a commercially available polymer-based diverse array of scaffolds for 3D in vitro tumor models. The RGD peptide present in these hydrogels enable cell attachment.
RGD sequences on extracellular matrix proteins (fibronectin, vitronectin) promote cell adhesion to cellular integrin receptors. The thiol group on the N-terminus of TrueGel3D® RGD peptide acts as linker to bind RGD motif to the polymer (Dextran/PVA). The conjugated RGD motif on polymer promotes adhesion of cells with appropriate integrin receptors.
Application
Polymer with cell adhesion motif (RGD) employed to generate cell-adhesive hydrogel
Features and Benefits
Contains cell adhesion motif RGD (Acetyl-Cys-Doa*-Doa-Gly-Arg-Gly-Asp-Ser-Pro-NH2), which binds to appropriate integrin receptors on cells.
*Doa : 8-amino-3,6-dioxaoctanoic acid
*Doa : 8-amino-3,6-dioxaoctanoic acid
Other Notes
TRUERGD contains RGD degradable polymer lyophilized and water
Legal Information
TRUEGEL3D is a registered trademark of Merck KGaA, Darmstadt, Germany
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This Item | |||
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| description Integrin Adhesion Peptide | description Modifed for slow gelling (SLO-PVA) | description PEG non cell-degradable crosslinker | description Integrin Adhesion Peptide |
| storage temp. −20°C | storage temp. −70°C | storage temp. −20°C | storage temp. −20°C |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
Storage Class
10 - Combustible liquids
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