The solution stability and storage of this product has not been tested, however other commercial sources offer 1M Trehalose solutions that are stored at ambient temperature or refrigerated (filter-sterilized). Trehalose is added to several of less stable protein preparations as a carrier and/or cryoprotectant. An example would be EGFR, E2645. This lyophilized product contains 10% Trehalose. Upon reconstitution the product can be stored for up to 1 year at -70 deg C. Given the information above, Trehalose may be quite stable in solution.
T0167
D-(+)-Trehalose dihydrate
from Saccharomyces cerevisiae, powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥99%
Synonym(s):
α,α-Trehalose, α-D-Glucopyranosyl-α-D-glucopyranoside
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All Photos(4)
About This Item
Empirical Formula (Hill Notation):
C12H22O11 · 2H2O
CAS Number:
Molecular Weight:
378.33
Beilstein:
5322018
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.75
Pricing and availability is not currently available.
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Quality Level
biological source
Saccharomyces cerevisiae
product line
BioReagent
Assay
≥99%
form
powder
technique(s)
cell culture | insect: suitable
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL
SMILES string
[H]O[H].[H]O[H].OC[C@H]1O[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
InChI
1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
InChI key
DPVHGFAJLZWDOC-PVXXTIHASA-N
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General description
Application
Biochem/physiol Actions
Trehalose is essential for embryogenesis, carbon metabolism, photosynthesis and flowering in plants. It predominantly exists among the species that supports anhydrobiosis (life without water).[1] It serves as a carbohydrate reserve in microorganisms and protects them from adverse conditions,[5] such as heat, cold, dehydration, desiccation and oxidation.[2] Trehalose acts as a chemical chaperone affecting protein folding. It is known to prevent amyloid generation and accummulation of β-amyloid in vitro. A similar effect of trehalose has been observed with huntingtin protein aggregation. Thus, it might serve as a protective agent in Alzheimer′s disease and Huntington′s disease.[2]
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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We would like to dissolve trehalose in water in bulk and store it. Does dissolved trehalose loose its stability after an extended storage time? Which storage temperature would you recommend?
1 answer-
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Can Product T0167, D-(+)-Trehalose dihydrate, be used as a substitute for protein in a freezing media?
1 answer-
Yes, it should work as a substitute for protein in a freezing media. It is commonly used at a final concentration of 5% (50 mg/mL). Alternatively, one could use methylcellulose.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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Do we have information of any fluorescent impurities in Product T0167, D-(+)-Trehalose dihydrate?
1 answer-
This product is not tested for the presence or absence of fluorescent impurities.
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Can solutions of Product T0167, D-(+)-Trehalose dihydrate, be autoclaved?
1 answer-
Do not autoclave. It is best to sterile filter solutions.
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Active Filters
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