SML2159

Minodronic acid monohydrate

≥98% (HPLC)

• Synonym(s): [1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethylidene]bisphosphonic acid monohydrate
• Empirical Formula (Hill Notation): C₉H₁₂N₂O₇P₂ · H₂O
• CAS Number: 155648-60-5
• Molecular Weight: 340.16
• UNSPSC Code: 12352106
• NACRES: NA.77
• MDL number: MFCD20037380
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: 0.1 M NaOH: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: OC(P(O)(O)=O)(P(O)(O)=O)CC1=CN=C2N1C=CC=C2.O
• InChI: 1S/C9H12N2O7P2.H2O/c12-9(19(13,14)15,20(16,17)18)5-7-6-10-8-3-1-2-4-11(7)8;/h1-4,6,12H,5H2,(H2,13,14,15)(H2,16,17,18);1H2
• InChI key: GPAPAOGRNKUFGH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Bone resorption inhibitor; inhibitor of farnesyl diphosphate synthase

Minodronate is a third-generation bisphosphonate used clinically alone or in combination to treat osteoporosis. It is an inhibitor of farnesyl diphosphate synthase that acts as a bone resorption inhibitor.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable