SML2053

Lalistat 2

≥98% (HPLC), lysosomal acid lipase (LAL) inhibitor, powder

• Synonym(s): 1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester, Lalistat-2
• Empirical Formula (Hill Notation): C₁₃H₂₀N₄O₂S
• CAS Number: 1234569-09-5
• Molecular Weight: 296.39
• UNSPSC Code: 41106300
• NACRES: NA.77
• MDL number: MFCD31544494
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Product Name: Lalistat 2, ≥98% (HPLC)
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C(N1CCCCC1)OC2=NSN=C2N3CCCCC3
• InChI key: PNYYVHOTXOEBEV-UHFFFAOYSA-N

Description

Application

Lalistat 2 has been used as a lysosomal acid lipase (LAL) inhibitor to study its effects on hypoxia-inducible factor (HIF) in mice. It has also been used as a LAL inhibitor to study LAL activity on dried blood spot cards.

Biochem/physiol Actions

Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization.

potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral