SML0308

Carbazeran

≥95% (HPLC), Aldehyde oxidase (AO) substrate, powder

• Synonym(s): N-Ethyl-carbamic acid 1-(6,7-dimethoxy-1-phthalazinyl)-4-piperidinyl ester, UK 31557
• Empirical Formula (Hill Notation): C₁₈H₂₄N₄O₄
• CAS Number: 70724-25-3
• Molecular Weight: 360.41
• UNSPSC Code: 41106305
• PubChem Substance ID: 329825313
• NACRES: NA.77
• MDL number: MFCD00867107
• Assay: ≥95% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Product Name: Carbazeran, ≥95% (HPLC)
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥2 mg/mL at warmed
• storage temp.: 2-8°C
• SMILES string: CCNC(=O)OC1CCN(CC1)c2nncc3cc(OC)c(OC)cc23
• InChI: 1S/C18H24N4O4/c1-4-19-18(23)26-13-5-7-22(8-6-13)17-14-10-16(25-3)15(24-2)9-12(14)11-20-21-17/h9-11,13H,4-8H2,1-3H3,(H,19,23)
• InChI key: QJGVXJYGDBSPSJ-UHFFFAOYSA-N

Description

General description

Carbazeran is usedin the treatment of heart failure.

Biochem/physiol Actions

Aldehyde oxidase (AO) substrate; inotropic agent and phosphodiesterase inhibitor

Carbazeran is an Aldehyde oxidase (AO) substrate and a phosphodiesterase inhibitor that produces concentration-dependent positive inotropic responses. In humans, the compound is almost completely cleared via 4-hydroxylation to the phthalazinone metabolite by AO.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Codes: H301
• Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable