Q1004

Quipazine maleate salt

serotonin/5-hydroxytryptamine-2A/C receptor agonist

• Synonym(s): 2-(1-Piperazinyl)quinoline maleate salt
• Empirical Formula (Hill Notation): C₁₃H₁₅N₃ · C₄H₄O₄
• CAS Number: 5786-68-5
• Molecular Weight: 329.35
• NACRES: NA.77
• PubChem Substance ID: 24278122
• UNSPSC Code: 12352200
• EC Number: 227-314-2
• MDL number: MFCD00133796

Properties

• Product Name: Quipazine maleate salt,
• Quality Segment: 200
• solubility: H₂O: soluble, alcohol: soluble, dilute aqueous acid: soluble
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C/C(O)=O.C1CN(CCN1)c2ccc3ccccc3n2
• InChI: 1S/C13H15N3.C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;5-3(6)1-2-4(7)8/h1-6,14H,7-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: QYJJDHZHSCTBII-BTJKTKAUSA-N
• Gene Information: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Description

Application

Quipazine maleate salt has been used as a serotonin receptor agonist to study its effects on mouse models with spinal cord injury.[1][2] It has also been used as a serotonin receptor agonist to study its effects on the locomotion of zebrafish.[3]

Biochem/physiol Actions

Quipazine belongs to the class of psychedelics[4] and acts as a serotonin/5-hydroxytryptamine-2A/C receptor agonist.[2] It also acts as an inhibitor of prolactin.[5]

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P301 + P310 + P330
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves