P7036
Parathyroid hormone human
≥92% (HPLC), powder
Synonym(s):
PTH, Parathormone
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About This Item
Empirical Formula (Hill Notation):
C408H674N126O126S2
CAS Number:
Molecular Weight:
9424.62
UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Biological source:
synthetic (organic)
Form:
powder
Assay:
≥92% (HPLC)
Pricing and availability is not currently available.
General description
Parathyroid hormone (PTH) is a circulating hormone secreted from the parathyroid gland. This hormone is synthesized as a pre-pro hormone. PTH is composed of binding regions that have a high affinity to a receptor and functional domains that interact with the receptors to initiate an intracellular signaling cascade.
Application
Parathyroid hormone human has been used to incubate mature human adipocytes.
Biochem/physiol Actions
Parathyroid hormone (PTH) exerts its effects on bone and kidney cells. This hormone plays a role in calcium homeostasis. PTH is secreted from the chief cells of the parathyroid gland in response to low extracellular calcium levels or higher levels of extracellular phosphate. PTH deficiency or excess PTH are associated with hypoparathyroidism and hyperparathyroidism, respectively.
Other Notes
Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-Val-Ala-Leu-Gly-Ala-Pro-Leu-Ala-Pro-Arg-Asp-Ala-Gly-Ser-Gln-Arg-Pro-Arg-Lys-Lys-Glu-Asp-Asn-Val-Leu-Val-Glu-Ser-His-Glu-Lys-Ser-Leu-Gly-Glu-Ala-Asp-Lys-Ala-Asp-Val-Asn-Val-Leu-Thr-Lys-Ala-Lys-Ser-Gln
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This Item | |||
|---|---|---|---|
| description ≥92% (HPLC), powder | description clone 4A2, purified immunoglobulin, buffered aqueous solution | description clone 4E10, purified immunoglobulin, buffered aqueous solution | description ≥97% (HPLC), powder |
| biological source synthetic (organic) | biological source mouse | biological source mouse | biological source - |
| assay ≥92% (HPLC) | assay - | assay - | assay ≥97% (HPLC) |
| Quality Level 200 | Quality Level 100 | Quality Level 100 | Quality Level 200 |
| form powder | form buffered aqueous solution | form buffered aqueous solution | form powder |
| Gene Information human ... PTH(5741) | Gene Information human ... PTH(5741) | Gene Information human ... PTH(5741) | Gene Information - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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