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P3683

Sigma-Aldrich

Paraplast Plus®

for tissue embedding

Synonym(s):

Paraffin – polyisobutylene mixture

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About This Item

CAS Number:
125387-89-5
EC Number:
232-315-6
MDL number:
MFCD00131795
UNSPSC Code:
12171500
NACRES:
NA.47

form

solid

mp

56-57 °C (lit.)
56-57 °C

application(s)

hematology
histology

storage temp.

room temp

General description

Paraplast Plus® is a tissue embedding medium comprising highly purified paraffin and polyisobutylene with approximately 0.8% DMSO added to improve infiltration, sectioning, and penetration into tissues. It is recommended for tissues that are difficult to process with regular Paraplast®. Paraplast Plus® cuts continuous ribbons at 2μm thickness or short ribbons at 1μm thickness.

Application

  • Paraplast Plus® has been used in the examination of vertebral specimens of Malacoraja senta.
  • It has also been used in the identification and expression analysis of PIN genes in rice.
  • It has been used in the study of glucose transport mechanisms in uterine tissues during pregnancy.
  • It has been used to embed Bouin′s fixed carp tissues, rat ventral prostatic fragments, and common bean (Phaseolus vulgaris L.) nodules.

Legal Information

Paraplast is a registered trademark of Leica Biosystems
Paraplast Plus is a registered trademark of Leica Biosystems

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Harmful effects of carbamazepine on the postnatal development of the rat ventral prostate
Samara U Oliva
Reproductive Biology and Endocrinology (2012)
Ellen C R Leonel et al.
Theriogenology, 105, 97-106 (2017-09-25)
Ovarian tissue transplantation could be a valuable technique for the preservation of endangered animals. The domestic cat affords an adequate experimental model for studies aimed at wild felids due to its phylogenetic similarity. Thus, this pilot study evaluated the efficacy
Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Yugantak Raj Gupta
Aquaculture International (2017)
Shuaibin Zhang et al.
Scientific reports, 6, 23173-23173 (2016-03-19)
Early fruit development is crucial for crop production in tomato. After fertilization, the ovary undergoes cell division and cell expansion before maturation. Although the roles of regulatory signals such as hormone and carbohydrate during early fruit development have been studied
Nozomu Yoshioka et al.
Disease models & mechanisms, 13(5) (2020-06-03)
Loss-of-function mutations in dystonin (DST) can cause hereditary sensory and autonomic neuropathy type 6 (HSAN-VI) or epidermolysis bullosa simplex (EBS). Recently, DST-related diseases were recognized to be more complex than previously thought because a patient exhibited both neurological and skin
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