H3261

2-Mercaptopyridine N-oxide sodium salt

≥96%

• Synonym(s): Sodium Omadine, Sodium pyrithione, 1-Hydroxy-2-pyridinethione sodium salt, 2-Mercaptopyridine-1-oxide sodium salt, 2-Pyridinethiol-1-oxide sodium salt, Pyrithione sodium salt
• Empirical Formula (Hill Notation): C₅H₄NNaOS
• CAS Number: 3811-73-2
• Molecular Weight: 149.15
• Beilstein: 4026050
• EC Number: 223-296-5
• MDL number: MFCD01941547
• UNSPSC Code: 51102829
• PubChem Substance ID: 24895565
• NACRES: NA.85

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥96%
• color: faintly beige; white to light yellow
• solubility: H₂O: 50 mg/mL
• antibiotic activity spectrum: fungi
• Mode of action: cell membrane | interferes
• SMILES string: [Na+].[O-][n+]1ccccc1[S-]
• InChI: 1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1
• InChI key: WNGMMIYXPIAYOB-UHFFFAOYSA-M

Description

Application

2-Mercaptopyridine N-oxide can be used to generate bidentate oxothiolane chelates with transition metals.

2-Mercaptopyridine N-oxide, also called pyrithione, is added to cells in culture so metals enter them readily without relying on transporters. It is used to study picornavirus infections.

Biochem/physiol Actions

2-Mercaptopyridine N-oxide is a zinc ionophore that transports zinc into cells.

Safety Information

• Pictograms: GHS06,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H311 + H331,H315,H317,H319,H372,H410
• Precautionary Statements: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P311 - P314
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1
• Target Organs: Nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves