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N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly

Name: N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly
Brand: SIGMA

chromogenic, ≥99% (HPLC)

Synonym(s):

FAPGG, N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₂₁N₃O₆

CAS Number:

64967-39-1

Molecular Weight:

399.40

UNSPSC Code:

12352202

PubChem Substance ID:

24894929

NACRES:

NA.32

MDL number:

MFCD00036816

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Properties

Product Name

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly,

Quality Segment

300

storage temp.

−20°C

SMILES string

OC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\c2ccco2

InChI

1S/C20H21N3O6/c24-17(9-8-15-7-4-10-29-15)23-16(11-14-5-2-1-3-6-14)20(28)22-12-18(25)21-13-19(26)27/h1-10,16H,11-13H2,(H,21,25)(H,22,28)(H,23,24)(H,26,27)/b9-8+/t16-/m0/s1

InChI key

ZDLZKMDMBBMJLI-FDMDGMSGSA-N

Gene Information

human ... ACE(1636), ACE2(59272)
mouse ... ACE3(217246)
rat ... ACE(11421), ACE2(70008), ACE3(498012)

Description

General description

A substrate for continuous spectrophotometric assay of angiotensin converting enzyme (ACE).

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly acts as a substrate for angiotensin converting enzyme (ACE), and is used in inhibitory assays of ACE.[1]

Application

N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly has been used for kinetic spectrophotometric assay of ACE (angiotensin converting enzyme) inhibitory activity.[2]

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This Item	F5135	G5779	G3882
Sigma-Aldrich F7131 N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly	Sigma-Aldrich F5135 N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala	Sigma-Aldrich G5779 Gly-Pro-Arg-Pro amide	Sigma-Aldrich G3882 Gly-Gly-Gly-Gly
Quality Level 300	Quality Level 200	Quality Level 200	Quality Level 200
Gene Information human ... ACE(1636), ACE2(59272) mouse ... ACE3(217246) rat ... ACE(11421), ACE2(70008), ACE3(498012)	Gene Information mouse ... Prkcq(18761)	Gene Information human ... FN1(2335) mouse ... FN1(14268) rat ... FN1(25661)	Gene Information -
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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