C0283

L-Carnitine hydrochloride

≥98%, synthetic

• Synonym(s): (−)-β-Hydroxy-γ-(trimethylammonio)butyrate, Vitamin B_T
• Linear Formula: (CH₃)₃N⁺CH₂CH(OH)CH₂CO₂H · Cl^-
• CAS Number: 6645-46-1
• Molecular Weight: 197.66
• NACRES: NA.79
• PubChem Substance ID: 24892246
• UNSPSC Code: 12352106
• EC Number: 229-663-6
• MDL number: MFCD00066100

Properties

• Product Name: L-Carnitine hydrochloride, synthetic, ≥98%
• biological source: synthetic
• Quality Segment: 300
• assay: ≥98%
• form: powder
• color: white
• mp: 142 °C
• application(s): cell analysis
• SMILES string: [Cl-].C[N+](C)(C)C[C@H](O)CC(O)=O
• InChI: 1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H/t6-;/m1./s1
• InChI key: JXXCENBLGFBQJM-FYZOBXCZSA-N

Description

Application

L-Carnitine hydrochloride has been used to study ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5. It has also been used to allow the entry of palmitic acid into the mitochondria.

Biochem/physiol Actions

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Carnitine is biosynthesized from lysine. It might be associated with the energy production from branched chain amino acids.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Codes: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): dust mask type N95 (US), Eyeshields, Gloves