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A6426

Sigma-Aldrich

Antifoam 204

mixture of organic polyether dispersions

Synonym(s):

organic antifoam

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About This Item

MDL number:
UNSPSC Code:
12161900
NACRES:
NA.25

biological source

synthetic

form

liquid

technique(s)

microbiological culture: suitable

viscosity

400 cP(lit.)

density

1.01 g/cm3 at 25 °C (lit.)

storage temp.

room temp

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General description

Antifoam function as an effective foam suppressor. Antifoam 204 contains 100% active components and is a mixture of organic non-silicone polypropylene-based polyether dispersions. It does not contain mineral oil. Antifoam 204 can itself be considered a surfactant, but it contains no other surfactants. This product is synthetic and not derived from animal or plant sources. Antifoam 204 can be sterilized repeatedly. The flow properties of Antifoam 204 are such that it can be pumped to a fermenter on an as-needed basis. For use in microbiological media, Sigma recommends a starting concentration of between 0.005% and 0.01%.

Application

Antifoam 204 has been used:

  • to suppress bubbling in thylakoid solutions during intramembrane isoprene quantification
  • as a component of fed-batch continuous culture fermentation medium
  • to suppress severe foaming in fermenter

Features and Benefits

  • Highly versatile surfactant for your cell biology and biochemical research
  • Suitable for microbiological culture

Other Notes

Contains 100% active components and is a mixture of non-silicone organic defoamers in a polyol dispersion. Can be sterilized repeatedly.
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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Juan J Barrero et al.
New biotechnology, 60, 85-95 (2020-10-13)
Pichia pastoris (Komagataella spp.) has become one of the most important host organisms for production of heterologous proteins of biotechnological interest, many of them extracellular. The protein secretion pathway has been recognized as a limiting process in which many roadblocks
Martin Kavšček et al.
BMC systems biology, 9, 72-72 (2015-10-28)
Yarrowia lipolytica is a non-conventional yeast that is extensively investigated for its ability to excrete citrate or to accumulate large amounts of storage lipids, which is of great significance for single cell oil production. Both traits are thus of interest
Vasil D'Ambrosio et al.
Metabolic engineering, 61, 369-380 (2020-07-28)
Engineering living cells for production of chemicals, enzymes and therapeutics can burden cells due to use of limited native co-factor availability and/or expression burdens, totalling a fitness deficit compared to parental cells encoded through long evolutionary trajectories to maximise fitness.
Ultrasound-assisted fermentation enhances bioethanol productivity
Sulaiman AZ, et al.
Biochemical Engineering Journal, 54(3), 141-150 (2011)
Physiology of Aspergillus niger in oxygen-limited continuous cultures: Influence of aeration, carbon source concentration and dilution rate
Diano A, et al.
Biotechnology and Bioengineering, 103(5), 956-965 (2009)

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