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A6112

Sigma-Aldrich

Calmodulin-Agarose

saline suspension

Synonym(s):

Calmodulin−Agarose, Phosphodiesterase 3′,5′-Cyclic Nucleotide Activator-Agarose from bovine testes

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About This Item

MDL number:
MFCD00165272
UNSPSC Code:
41106500
NACRES:
NA.56

biological source

Saccharomyces cerevisiae

Quality Level

200

form

saline suspension

extent of labeling

≥0.5 mg per mL

technique(s)

affinity chromatography: suitable

matrix

4% beaded agarose

matrix activation

cyanogen bromide

matrix attachment

amino

matrix spacer

1 atom

suitability

suitable for chromatography

storage temp.

2-8°C

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Application

Calmodulin-agarose is used in affinity chromatography, protein chromatography, calcium associated proteins, and specialty resins. Calmodulin-agarose has been used to suggest a coordinated regulation of processes in both mitochondria and chloroplasts by calcium signals. Calmodulin-agarose has also been used to study apoptosis in prostate cancer cells and to analyze the interaction of the influenza virus polymerase complex with human cell factors.

Physical form

Suspension in 0.5 M NaCl containing preservative

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
0000382461
0000382461
SLCL1269
SLCJ3403
SLBX2956

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Ninghai Gan et al.
Nature, 572(7769), 387-391 (2019-07-23)
The bacterial pathogen Legionella pneumophila creates an intracellular niche permissive for its replication by extensively modulating host-cell functions using hundreds of effector proteins delivered by its Dot/Icm secretion system1. Among these, members of the SidE family (SidEs) regulate several cellular

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