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A0278

L-Ascorbic acid

reagent grade

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

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About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
Molecular Weight:
176.12
UNSPSC Code:
12352209
NACRES:
NA.26
PubChem Substance ID:
EC Number:
200-066-2
Beilstein/REAXYS Number:
84272
MDL number:
Assay:
≥98% (with Iodine, titration)
Form:
powder
Grade:
reagent grade
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biological source

synthetic

Quality Segment

grade

reagent grade

assay

≥98% (with Iodine, titration)

form

powder

technique(s)

HPLC: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. It is a water-soluble vitamin.

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.
L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals. It may be used for the reduction of graphene oxide sheets.[1]

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals. It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory.[1] Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.[2]
L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration. It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.

Disclaimer

May darken in storage.

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This Item
A596095212A2218
grade

reagent grade

grade

-

grade

-

grade

-

assay

≥98% (with Iodine, titration)

assay

≥99.0%

assay

99.0-100.5%

assay

99.0-100.5%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

crystalline

form

solid

form

solid

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

pH

1.0-2.5 (25 °C, 176 g/L in water)

solubility

water: soluble 50 mg/mL

solubility

H2O: 0.5 M, clear, colorless

solubility

water: soluble 176 g/L at 20 °C

solubility

water: soluble 176 g/L at 20 °C


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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