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82553

Sigma-Aldrich

Pterine-6-carboxylic acid

≥98.0% (HPLC)

Synonym(s):

2-Amino-4-hydroxypteridine-6-carboxylicacid

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About This Item

Empirical Formula (Hill Notation):
C7H5N5O3
CAS Number:
948-60-7
Molecular Weight:
207.15
Beilstein:
227689
EC Number:
213-435-8
MDL number:
MFCD00010594
UNSPSC Code:
12352106
PubChem Substance ID:
57652920
NACRES:
NA.79

biological source

synthetic

Quality Level

100

Assay

≥98.0% (HPLC)

form

powder or crystals

color

white to faint yellow

storage temp.

2-8°C

SMILES string

NC1=Nc2ncc(nc2C(=O)N1)C(O)=O

InChI

1S/C7H5N5O3/c8-7-11-4-3(5(13)12-7)10-2(1-9-4)6(14)15/h1H,(H,14,15)(H3,8,9,11,12,13)

InChI key

QABAUCFGPWONOG-UHFFFAOYSA-N

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Other Notes

Review: Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 21(9), 2101-2107 (2007-03-08)
The known functions of folate are to support one-carbon metabolism and to serve as photoreceptors for cryptochromes and photolyases. We demonstrate that 5-methyltetrahydrofolate (5-MTHF, the predominant folate in plasma) is also a potent, near diffusion limited, scavenger of singlet oxygen
M J Akhtar et al.
Journal of pharmaceutical and biomedical analysis, 23(6), 1039-1044 (2000-11-30)
A study of the photolysis of folic acid in aqueous solution by visible radiation in the presence of riboflavin has been made. The second-order rate constants for the bimolecular interaction of folic acid and riboflavin have been determined in the
Ilja Gasan Osojnik Črnivec et al.
Food & function, 11(2), 1467-1477 (2020-01-25)
Encapsulation provides efficient approaches to increase stability and delivery of poorly soluble bioactive components, predominantly for fortification of beverages and similar liquid-based foods. In this study, folic acid was encapsulated within conventional and emulsion-templated alginate-pectin hydrogels, proliposomes, and a combination
Kazutaka Hirakawa et al.
Archives of biochemistry and biophysics, 410(2), 261-268 (2003-02-08)
DNA damage mediated by photosensitizers participates in solar carcinogenesis. Fluorescence measurement and high-performance liquid chromatography analysis demonstrated that photoirradiated folic acid, one of the photosensitizers in cells, generates pterine-6-carboxylic acid (PCA). Experiments using 32P-labeled DNA fragments obtained from a human
Biosynthesis and metabolism of tetrahydrobiopterin and molybdopterin.
C A Nichol et al.
Annual review of biochemistry, 54, 729-764 (1985-01-01)
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