54274

Chelidonine

≥97.0% (HPLC)

• Synonym(s): Stylophorin
• Empirical Formula (Hill Notation): C₂₀H₁₉NO₅
• CAS Number: 476-32-4
• Molecular Weight: 353.37
• NACRES: NA.77
• PubChem Substance ID: 329758025
• UNSPSC Code: 12352202
• EC Number: 207-504-1
• MDL number: MFCD00069660
• Assay: ≥97.0% (HPLC)
• Form: solid

Properties

• Quality Segment: 100
• assay: ≥97.0% (HPLC)
• form: solid
• impurities: ~5% water
• storage temp.: 2-8°C
• SMILES string: [H][C@]12[C@@H](O)Cc3cc4OCOc4cc3[C@@]1([H])N(C)Cc5c6OCOc6ccc25
• InChI: 1S/C20H19NO5/c1-21-7-13-11(2-3-15-20(13)26-9-23-15)18-14(22)4-10-5-16-17(25-8-24-16)6-12(10)19(18)21/h2-3,5-6,14,18-19,22H,4,7-9H2,1H3/t14-,18-,19+/m0/s1
• InChI key: GHKISGDRQRSCII-ZOCIIQOWSA-N

Description

Biochem/physiol Actions

Inhibits tubulin polymerisation (IC₅₀=24 μM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301 + H331
• pcodes: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves