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50020

β-Glycerol phosphate disodium salt pentahydrate

≥98.0% (NT)

Synonym(s):

β-GP, β-glycerolphosphate, Disodium β-glycerol phosphate pentahydrate, glycerol-2-phosphate

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About This Item

Empirical Formula (Hill Notation):
C3H7Na2O6P · 5H2O
CAS Number:
Molecular Weight:
306.11
UNSPSC Code:
41141710
NACRES:
NA.25
PubChem Substance ID:
EC Number:
212-464-3
Beilstein/REAXYS Number:
3744328
MDL number:
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Quality Level

assay

≥98.0% (NT)

form

solid

impurities

≤2% L-α-glycerol phosphate

loss

26-32% loss on drying

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

2-8°C

SMILES string

O.O.O.O.O.[Na+].[Na+].OCC(CO)OP([O-])([O-])=O

InChI

1S/C3H9O6P.2Na.5H2O/c4-1-3(2-5)9-10(6,7)8;;;;;;;/h3-5H,1-2H2,(H2,6,7,8);;;5*1H2/q;2*+1;;;;;/p-2

InChI key

PEMUISUYOHQFQH-UHFFFAOYSA-L

Application

β-Glycerolphosphate (Glycerol-2-Phosphate) is used in the development of hydrogels and scaffolds that have applications in tissue engineering and cell growth and differentiation.

Biochem/physiol Actions

Beta-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It functions as an organic phosphate donor and has been used in culture media for mesenchymal stem cell differentiation to osteoblast-type cells. BGP is also used to buffer M17 media for Lactococcus culture in recombinant protein expression

Other Notes

Substrate for myo-inositol-1-phosphatase from bovine brain[1]

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This Item
61668G542235675
assay

≥98.0% (NT)

assay

≥95.0% (TLC), 95-102% anhydrous basis (corrected for sodium, T)

assay

-

assay

≥97% (titration)

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

100

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

-

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 5 mg/mL

form

solid

form

powder or solid

form

powder

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

impurities

≤2% L-α-glycerol phosphate

impurities

≤35% water

impurities

≤0.1% Inorganic phosphorus, ≤1.0 mol % L-α-isomer

impurities

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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A Sanghani-Kerai et al.
Bone & joint research, 6(6), 358-365 (2017-06-04)
Cellular movement and relocalisation are important for many physiologic properties. Local mesenchymal stem cells (MSCs) from injured tissues and circulating MSCs aid in fracture healing. Cytokines and chemokines such as Stromal cell-derived factor 1(SDF-1) and its receptor chemokine receptor type
Yung-Hsin Cheng et al.
Tissue engineering. Part A, 16(2), 695-703 (2009-09-23)
Injectable hydrogel is one of the great interests for tissue engineering and cell encapsulation. In the study, the gelatin molecules were added to the thermosensitive chitosan/beta-glycerol phosphate (C/GP) disodium salt hydrogels to form chitosan/gelatin/beta-glycerol phosphate (C/G/GP) disodium salt hydrogels which
Cristiane Machado Mengatto et al.
PloS one, 6(1), e15848-e15848 (2011-01-26)
Successful dental and orthopedic implants require the establishment of an intimate association with bone tissue; however, the mechanistic explanation of how biological systems accomplish osseointegration is still incomplete. We sought to identify critical gene networks involved in osseointegration by exploring



Global Trade Item Number

SKUGTIN
50020-100G04061832422466
50020-500G04061832422473

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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