80822

(S)-Naproxen methyl ester

pharmaceutical impurity standard

• Synonym(s): Naproxen Impurity E (PhEur), (2S)-2-(6-Methoxy-2-naphthyl)propionic acid methyl ester, Methyl (αS)-6-methoxy-α-methyl-2-naphthaleneacetate, Methyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
• Empirical Formula (Hill Notation): C₁₅H₁₆O₃
• CAS Number: 26159-35-3
• Molecular Weight: 244.29
• UNSPSC Code: 12352108
• NACRES: NA.24
• PubChem Substance ID: 329769059
• MDL number: MFCD12031841
• Beilstein/REAXYS Number: 4352971

Properties

• Quality Segment: 100
• API family: naproxen
• assay: ≥98.0% (HPLC)
• optical activity: [α]/D 72.0 to 84.0°, c = 0.1 in chloroform
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤0.5% water
• mp: 87 °C
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: C[C@H](C(OC)=O)C1=CC2=CC=C(OC)C=C2C=C1
• InChI: 1S/C15H16O3/c1-10(15(16)18-3)11-4-5-13-9-14(17-2)7-6-12(13)8-11/h4-10H,1-3H3/t10-/m0/s1
• InChI key: ZFYFBPCRUQZGJE-JTQLQIEISA-N

Description

General description

(S)-Naproxen methyl ester is an ester of the non-steroidal, anti-inflammatory drug, (S)-naproxen

Safety Information

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361fd,H411
• pcodes: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable