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17814

Sigma-Aldrich

Lactose

tested according to Ph. Eur.

Synonym(s):

Lactosum

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About This Item

Empirical Formula (Hill Notation):
C12H22O11
CAS Number:
63-42-3
Molecular Weight:
342.30
Beilstein:
93796
EC Number:
200-559-2
MDL number:
MFCD00151251
UNSPSC Code:
12352201
PubChem Substance ID:
329751569
NACRES:
NA.21
Pricing and availability is not currently available.

Agency

USP/NF
tested according to Ph. Eur.

Quality Level

100
200

form

solid

SMILES string

OC[C@@H](O)[C@@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@@H](O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h1,4-12,14-21H,2-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1

InChI key

DKXNBNKWCZZMJT-JVCRWLNRSA-N

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Related Categories

Application


  • Galectin-receptor interaction: a key player in liver fibrosis induced by Schistosoma japonicum infection.: This study explores the impact of galectin-receptor interactions on liver fibrosis caused by Schistosoma japonicum, potentially impacting lactose metabolism pathways involved in liver health (Huang et al., 2024).


Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL6300
BCCK6855
BCCK0466
BCCJ3664
BCCH7214

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T M Bayless et al.
The New England journal of medicine, 292(22), 1156-1159 (1975-05-29)
We studied 166 hospitalized male patients to determine the clinical importance of tolerance-test-determined "lactose intolerance," assumed to affect most of the world's adults. Abnormal lactose tolerance tests were found in 81% of 98 blacks, 12% of 59 whites of Scandinavian
J Boya et al.
Journal of anatomy, 175, 229-236 (1991-04-01)
A lectin-histochemical study on microglial development has been performed on the rat central nervous system. Isolectin B4 from the Griffonia simplicifolia (GSA I-B4) and Ricinus communis agglutinin-120 (RCA-1) were used as labelling lectins. Our results demonstrate the existence of microglial
P Wong et al.
Biotechnology progress, 13(2), 132-143 (1997-03-01)
A mathematical model of the lactose (lac) operon was developed to study diauxic growth on glucose and lactose. The model includes catabolite repression, inducer exclusion, lactose hydrolysis to glucose and galactose, and synthesis and degradation of allolactose. Two models for
C L Wells et al.
Infection and immunity, 55(11), 2689-2694 (1987-11-01)
It is thought that the normal enteric microflora acts not only to prevent intestinal colonization but also to prevent subsequent systemic dissemination of ingested, potentially pathogenic bacteria. To determine the relative roles of specific components of the intestinal bacterial flora
Lactose intolerance following extensive small intestinal resection.
A J Richards et al.
The British journal of surgery, 58(7), 493-494 (1971-07-01)
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Chromatograms

application for HPLC

Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the dielectric constant ( relative permittivity) of this excipient?

    1 answer

    1. The dielectric constant of this product is not tested. A paper provides the real and imaginary parts of the alpha-lactose dielectric constant in the frequency range of 0.45–0.6 THz, which can serve as a reference: https://www.mdpi.com/2304-6732/9/11/848

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  4. Does the supporting documentation (SDS, CoA, or CoO) provide the actual purity value for the product, despite meeting the European Pharmacopoeia quality standards?

    1 answer

    1. Purity testing has not been conducted. Other Lactose anhydrous products were checked and none of them are tested for purity. There are lactose monohydrate products that are tested for purity by HPLC. Purity is simply not a specification for product 17814. Since there is no specification for purity, no testing is performed for purity.

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