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03971

Sigma-Aldrich

Hematoxylin solution according to Delafield

for microscopy

Synonym(s):

Delafield’s hematoxylin

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About This Item

Beilstein:
91401
MDL number:
MFCD00078111
UNSPSC Code:
12171500
PubChem Substance ID:
329747850
NACRES:
MA.02

grade

for microscopy

Quality Level

100

product line

BioChemika

form

liquid

technique(s)

microbe id | staining: suitable

impurities

ammonium alum
 methanol

density

0.950-1.044 g/mL at 20 °C

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

suitability

Chlamydia spp.
Histoplasma spp.
Plasmodium spp.
Trichomonas spp.
bacteria
protozoa
spirochetes

SMILES string

Oc1cc2C[C@@]3(O)COc4c(O)c(O)ccc4[C@H]3c2cc1O

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1

InChI key

WZUVPPKBWHMQCE-XJKSGUPXSA-N

General description

Hematoxylin solution according to Delafield is a naturally ripened alum hematoxylin with potassium alum or ammonium alum as the mordant. It is used when the counterstain doesn′t possess any acid content in it. It is suitable to be used as a nuclear stain with eosin.

Application

Hematoxylin solution according to Delafield has been used to stain the nuclei of different sections of adipose tissue for its histochemical analysis. It is suitable for staining thick or thin blood films. It is also frequently used to stain and study the visibility of microfilariae.

Signal Word

Danger

Hazard Statements

H226,H302,H370

Hazard Classifications

Acute Tox. 4 Oral - Flam. Liq. 3 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

107.6 °F - closed cup

Flash Point(C)

42 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL7402
BCCJ6439
BCCG5880
BCCC9816
BCCC8871

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Lijun Dong et al.
Inflammation, 40(6), 1944-1958 (2017-09-04)
T cells are involved in chronic inflammation of adipose tissue in obese conditions. However, the impact of age on the adipose T cells remains unknown. In this study, we investigated T cells in the white adipose tissue of young and
Niina Vuokila et al.
Cellular and molecular life sciences : CMLS, 75(24), 4557-4581 (2018-08-30)
Traumatic brain injury (TBI) initiates molecular and cellular pathologies that underlie post-injury morbidities, including hippocampus-related memory decline and epileptogenesis. Non-coding small RNAs are master regulators of gene expression with the potential to affect multiple molecular pathways. To evaluate whether hippocampal
Hongling Zhu et al.
Experimental and therapeutic medicine, 14(4), 3609-3615 (2017-10-19)
Basic fibroblast growth factor (bFGF), a known angiogenic factor, may provide a potential strategy for the treatment of myocardial infarction (MI), but it is limited by a relatively short half-life. Dex-PCL-HEMA/PNIPAAm hydrogel provides a reservoir for the controlled release of
Li-Gen Lin et al.
Journal of medicinal chemistry, 51(15), 4419-4429 (2008-07-10)
Protein tyrosine kinase (PTK) inhibitors represent emerging therapeutics for cancer chemoprevention. In our study, hematoxylin (26) was identified as one of the most remarkable c-Src inhibitors in an orthogonal compound-mixing library (32200 compounds) by using an ELISA-based automated high-throughput screening
Hideki Ishii et al.
Bioorganic & medicinal chemistry letters, 22(3), 1469-1474 (2012-01-17)
SAR studies for the exploration a novel class of anti-human immunodeficiency virus type 1 (HIV-1) agents based on the hematoxylin structure (1) are described. The systematic deoxygenations of 1 including asymmetric synthesis were conducted to obtain a compound showing high
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