8.22149

Tetraethylammonium hydroxide

(20% aqueous solution) for synthesis

• Synonym(s): TEA hydroxide
• NACRES: NA.22
• UNSPSC Code: 12352107
• Assay: 19.0 - 21.0% %
• Form: liquid

Properties

• Quality Segment: 200
• assay: 19.0 - 21.0% %
• form: liquid
• reaction suitability: core: ammonium
• pH: >13 (20 °C in H₂O)
• bp: 102 °C/1013 hPa
• mp: <-25 °C
• transition temp: flash point >110 °C
• density: 1.01 g/cm³ at 20 °C
• storage temp.: 2-30°C

Description

Application

• Mizoroki-Heck coupling: It serves as a solid, easy-to-handle ethylene precursor in Mizoroki-Heck coupling reactions, highlighting its application in facilitating complex organic synthesis processes (Papaplioura et al., 2024).
• Pharmacokinetic parameter prediction: It is involved in the synthesis and characterization of tetraalkylammonium salts for the pharmaceutical application of non-steroidal anti-inflammatory drugs, assisting in the in silico prediction of their pharmacokinetic parameters (Rybczyńska and Sikorski, 2023).

Analysis Note

Assay (acidimetric): 19.0 - 21.0 %
Density (d 20 °C/ 4 °C): 1.006 - 1.011

Safety Information

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H290,H312,H314,H370,H372
• pcodes: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1 - STOT RE 1 Dermal - STOT SE 1
• target_organs: Central nervous system, thymus,Liver
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• flash_point_f: >230.0 °F
• flash_point_c: > 110 °C