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C7263

Sigma-Aldrich

Calcium phosphate dibasic

98.0-105.0%

Synonym(s):

Calcium hydrogen phosphate

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About This Item

Linear Formula:
CaHPO4
CAS Number:
Molecular Weight:
136.06
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

98.0-105.0%

form

powder

SMILES string

[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+2;/p-2

InChI key

FUFJGUQYACFECW-UHFFFAOYSA-L

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Application

Calcium phosphate dibasic has been used:
  • to prepare high temperature stoichiometric sintered hydroxyapatite (sin-HA)
  • as a component of calcium phosphate cement (CPC) to prepare bioartificial pancreas (BAP)
  • to produce calcium pyrophosphate (Ca2P2O7) for the preparation of α-tricalcium phosphates (α-TCP)

Biochem/physiol Actions

Calcium phosphate dibasic is an anhydrate used to dilute tablets and capsules. It is widely used as an excipient for its compressibility, amenability, and brittle fracture propensity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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This article presents the application of dual focused ion beam/scanning electron microscopy (FIB-SEM) imaging for preclinical testing of calcium phosphates with osteoclast precursor cells and how this high-resolution imaging technique is able to reveal microstructural changes at a level of
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Journal of pharmaceutical sciences, 100(4), 1456-1466 (2011-04-01)
Dibasic calcium phosphate occurs as an anhydrate (DCPA; CaHPO₄) and as a dihydrate (DCPD; CaHPO₄•2H₂O). Our objective was to investigate the unusual behavior of these phases. Dibasic calcium phosphate dihydrate was dehydrated in a (i) differential scanning calorimeter (DSC) in
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