A3913
L-Argininamide dihydrochloride
≥98%, suitable for ligand binding assays
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About This Item
Empirical Formula (Hill Notation):
C6H15N5O · 2HCl
CAS Number:
Molecular Weight:
246.14
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
Recommended Products
Product Name
L-Argininamide dihydrochloride,
Assay
≥98%
Quality Level
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
Cl.N[C@@H](CCCNC(N)=N)C(N)=O
InChI
1S/C6H15N5O.ClH/c7-4(5(8)12)2-1-3-11-6(9)10;/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11);1H/t4-;/m0./s1
InChI key
BPQLYFCEVVKLLX-WCCKRBBISA-N
Application
L-Argininamide dihydrochloride has been used as an additive to compare its effect over L-arg in egg lysozyme refolding studies. It has also been used as a component of substrate stock solution for enzymatic kyotorphin synthesis.
Biochem/physiol Actions
L-Argininamide (L-Arm) is a hydrophilic amino acid derivative that is used as a model compound in physicochemical characteristic studies of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - STOT SE 1
Target Organs
Eyes
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Levitsky et al.
Enzyme and microbial technology, 26(8), 608-613 (2000-05-04)
Design of enzymatic kyotorphin synthesis in low water media has been carried out as a function of enzyme nature, the immobilization support material and the reaction medium, by using N-benzoyl-L-tyrosine ethyl ester and L-argininamide as substrates. Native and chemically-glycated alpha-chymotrypsin
Qi Zhang et al.
Science (New York, N.Y.), 311(5761), 653-656 (2006-02-04)
Using a domain elongation strategy, we decoupled internal motions in RNA from overall rotational diffusion. This allowed us to site-specifically resolve a manifold of motional modes in two regulatory RNAs from HIV-1 with the use of nuclear magnetic resonance spin
RNA dynamics by design: biasing ensembles towards the ligand-bound state.
Andrew C Stelzer et al.
Angewandte Chemie (International ed. in English), 49(33), 5731-5733 (2010-06-29)
Label-free aptamer-based sensors for L-argininamide by using nucleic acid minor groove binding dyes.
Zece Zhu et al.
Chemical communications (Cambridge, England), 47(11), 3192-3194 (2011-01-29)
The nucleic acid minor groove binding dyes, DAPI and Hoechst 33258, were for the first time used in label-free aptamer-based sensors for L-argininamide. The synergy binding effect results in the enhancement of fluorescence of dyes. The method for detection of
Tao Li et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 13(23), 6718-6723 (2007-05-17)
We report a novel label-free method for the investigation of the adaptive recognition of small molecules by nucleic acid aptamers using capillary electrophoresis analysis. Cocaine and argininamide were chosen as model molecules, and the two corresponding DNA aptamers were used.
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