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30461

Sigma-Aldrich

DEAE-Dextran hydrochloride

BioReagent, for molecular biology

Synonym(s):

Diethylaminoethyl-dextran hydrochloride

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About This Item

CAS Number:
9064-91-9
MDL number:
MFCD00081561
UNSPSC Code:
12352201
NACRES:
NA.25

grade

for molecular biology

Quality Level

100

product line

BioReagent

form

solid

impurities

DNases, none detected
 RNases, none detected
 phosphatases, none detected
 proteases, none detected

solubility

H2O: 0.1 g/mL, clear

storage temp.

room temp

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Application

DEAE-Dextran, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF8182
BCBZ8251
BCCB3123
BCBN1143V
1396877

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Transfection using DEAE-dextran.
Gulick T.
Current Protocols in Cell Biology, doi: 10-doi: 10 (2003)
S Tabor et al.
Current protocols in immunology, Chapter 10, Unit 10-Unit 10 (2008-04-25)
Extensive knowledge of the enzymology involved in biosynthesis and degradation of nucleic acids has permitted the development of simple methods for labeling RNA and DNA with radioisotopes or biotin. These labeled probes are used primarily for hybridization to nucleic acid
DEAE-dextran transfection of lymphocyte cell lines.
Smale ST.
Cold Spring Harbor Protocols, doi: 10-doi: 10 (2010)
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
Yoshimitsu Doi et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(24), 8381-8386 (2008-06-14)
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) mediated by Th17 and Th1 cells. DNA microarray analysis previously showed that NR4A2, an orphan nuclear receptor, is strongly up-regulated in the peripheral blood T cells of
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Related Content

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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