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908622

Sigma-Aldrich

Poly(lactide-co-glycolide)-Rhodamine B

lactide:glycolide 50:50, Mn 10,000-30,000

Synonym(s):

PLGA, PLGA-Rhodamine B

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About This Item

Linear Formula:
[C3H4O2]x[C2H2O2]y
UNSPSC Code:
12352116
NACRES:
NA.23
Pricing and availability is not currently available.

form

powder or chunks

feed ratio

lactide:glycolide 50:50

mol wt

Mn 10,000-30,000
average Mn 10,000-30,000

composition

Dye Content, 3.12 μg/mg (polymer)

color

red to maroon

storage temp.

−20°C

Related Categories

Application

This fluorescein labeled PLGA is a biocompatible and biodegradable polymer. It can be used in the formation of fluorescent nanoparticles for drug delivery and bioimaging applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW8415
MKCW2368
MKCT1702
MKCS7417
MKCK6033

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Yihan Xu et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 105(6), 1692-1716 (2016-04-22)
Poly (lactic-co-glycolic acid) (PLGA) copolymers have been broadly used in controlled drug release applications. Because these polymers are biodegradable, they provide an attractive option for drug delivery vehicles. There are a variety of material, processing, and physiological factors that impact
R Gref et al.
Science (New York, N.Y.), 263(5153), 1600-1603 (1994-03-18)
Injectable nanoparticulate carriers have important potential applications such as site-specific drug delivery or medical imaging. Conventional carriers, however, cannot generally be used because they are eliminated by the reticulo-endothelial system within seconds or minutes after intravenous injection. To address these

Questions

1–2 of 2 Questions  

  1. Could you provide information about the viscosity of this PLGA? Do you offer other PLGA options with different molecular weights (Mn) in your portfolio?

    1 answer

    1. The viscosity of this specific PLGA product has not been determined or provided. And there are no other PLGA-Rhodamine B products with different molecular weights (Mn) available in the current portfolio.

      Helpful?

  2. Is the Rhodamine B chemically bonded to the PLGA or is it just stuck inside the polymer matrix? Thanks

    1 answer

    1. The PLGA is covalently bonded to the Rhodamine B.

      Helpful?

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