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502332

Supelco

Benzo[j]fluoranthene solution

certified reference material, 2000 μg/mL in dichloromethane

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About This Item

Empirical Formula (Hill Notation):
C20H12
CAS Number:
205-82-3
Molecular Weight:
252.31
UNSPSC Code:
12000000

grade

certified reference material
TraceCERT®

Quality Level

300

product line

TraceCERT®

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

concentration

2000 μg/mL in dichloromethane

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

single component solution

storage temp.

2-30°C

InChI

1S/C20H12/c1-2-8-15-13(5-1)11-12-17-16-9-3-6-14-7-4-10-18(19(14)16)20(15)17/h1-12H

InChI key

KHNYNFUTFKJLDD-UHFFFAOYSA-N

General description

Benzo[j]fluoranthene is a polycyclic aromatic hydrocarbon, which is carcinogenic in nature and can be generated into the environment via combustion of coal, coal tar and petroleum products.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H336,H350,H412

Hazard Classifications

Aquatic Chronic 3 - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD6018
LRAD3904
LRAC5973
LRAB8520
XA26093V

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A Comprehensive Guide to the Hazardous Properties of Chemical Substances (2007)
Report on Carcinogens (12th Ed. ) (2011)
E J LaVoie et al.
Cancer letters, 70(1-2), 7-14 (1993-06-15)
Exceptional tumorigenic potency was observed with 4-fluorobenzo[j]fuoranthene (4-fluoroB[j]F) relative to benzo[j]fluoranthene (B[j]F) and 10-fluorobenzo[j]fluoranthene (10-fluoroB[j]F) in a mouse skin initiation promotion bioassay. Comparison of the tumorigenic response obtained at total initiating doses of 50, 100, and 1000 nmol firmly established
B D Silverman et al.
Chemico-biological interactions, 47(3), 289-292 (1983-12-01)
The benzo- and dibenzofluoranthenes, widespread environmental contaminants, have been subjects of continued interest. Calculations of the reactivity of potential ultimate carcinogenic metabolites of the benzofluoranthenes predict unexpected behavior for these non-alternant hydrocarbons.
E H Weyand et al.
Chemical research in toxicology, 6(1), 117-124 (1993-01-01)
Studies have demonstrated that the metabolic activation of benzo[j]fluoranthene (B[j]F) to a genotoxic agent proceeds through the formation of either the trans-4,5-dihydrodiol (B[j]F-4,5-diol) or the trans-9,10-dihydrodiol (B[j]F-9,10-diol) metabolite of B[j]F. Using 32P-postlabeling analysis, the profiles of DNA adducts formed in
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