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M6940

Sigma-Aldrich

Modafinil

≥98% (HPLC)

Synonym(s):

2-[(Diphenylmethyl)sulfinyl]­acetamide

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About This Item

Empirical Formula (Hill Notation):
C15H15NO2S
CAS Number:
68693-11-8
Molecular Weight:
273.35
MDL number:
MFCD00868082
UNSPSC Code:
12352200
PubChem Substance ID:
24897132
NACRES:
NA.77
Pricing and availability is not currently available.

Quality Level

100

Assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule IV

color

white

solubility

DMSO: >10 mg/mL

originator

Teva

SMILES string

NC(=O)CS(=O)C(c1ccccc1)c2ccccc2

InChI

1S/C15H15NO2S/c16-14(17)11-19(18)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H2,16,17)

InChI key

YFGHCGITMMYXAQ-UHFFFAOYSA-N

Gene Information

human ... SLC6A3(6531)
rat ... Slc6a3(24898)

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Biochem/physiol Actions

Modafinil is a central nervous system vigilance promoting agent, which posseses neuroprotective properties.

Features and Benefits

This compound was developed by Teva. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H361d

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000038704
0000207777
0000207777
0000207778
0000207778

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Kousuke Okimura et al.
Scientific reports, 11(1), 1843-1843 (2021-01-21)
At high latitudes, approximately 10% of people suffer from depression during the winter season, a phenomenon known as seasonal affective disorder (SAD). Shortened photoperiod and/or light intensity during winter season are risk factors for SAD, and bright light therapy is
Modafinil and armodafinil in schizophrenia.
Chittaranjan Andrade
The Journal of clinical psychiatry, 73(8), e1062-e1064 (2012-09-13)
Management of cognition and fatigue.
Susan M Rubin
Disease-a-month : DM, 59(7), 269-272 (2013-06-22)
Hypersomnia due to bilateral thalamic lesions: unexpected response to Modafinil.
I Zavalko et al.
European journal of neurology, 19(11), e125-e126 (2012-08-21)
Tristan Shuman et al.
Behavioural brain research, 235(2), 105-112 (2012-09-12)
Modafinil is a wake-promoting drug effective at enhancing alertness and attention with a variety of approved and off-label applications. The mechanism of modafinil is not well understood but initial studies indicated a limited abuse potential. A number of recent publications
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