Skip to Content
Merck
All Photos(1)

Key Documents

ABN472

Sigma-Aldrich

Anti-TFEB Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35, TFEB

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TFEB(7942)

Related Categories

General description

Transcription factor EB (TFEB) is a member of the MiT/TFE family of transcription factors that is translocated in a subset of renal tumors. It plays an important role in the signal transduction process required for normal vascularization of the placenta. TFEB specifically recognizes and binds the E-box sequence (5′-CANNTG-3′) and CLEAR box sequence (5′-GTCACGTGAC-3′).

Immunogen

KLH-conjugated linear peptide corresponding to human TFEB.

Application

Detect TFEB using this rabbit polyclonal antibody, Anti-TFEB Antibody validated for use in western blotting.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Quality

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TFEB in 15 µg of A549 cell lysate.

Target description

~57 kDa observed. Uniprot describes two isoforms at ~44 kDa and ~53 kDa Uncharacterized bands may appear in some lysates.

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
A549 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service