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1.12393

Sigma-Aldrich

Vanadium(III) chloride

99+

Synonym(s):

Vanadium(III) chloride, Vanadium trichloride

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About This Item

Empirical Formula (Hill Notation):
Cl3V
CAS Number:
7718-98-1
Molecular Weight:
157.30
MDL number:
MFCD00011454
UNSPSC Code:
12352302
EC Index Number:
231-744-6
NACRES:
NA.22

Quality Level

200

form

solid

potency

350 mg/kg LD50, oral (Rat)

density

3.0 g/cm3 at 20 °C

bulk density

1000 kg/m3

storage temp.

no temp limit

InChI

1S/3ClH.V/h3*1H;/q;;;+3/p-3

InChI key

HQYCOEXWFMFWLR-UHFFFAOYSA-K

Related Categories

Application

Vanadium(III) chloride (VCl3) can be used as a catalyst to synthesize:
  • Dihydropyrimidinone derivatives via a three-component Biginelli condensation reaction between aldehyde, β-keto ester, and urea (thiourea).
  • Coumarin derivatives via Pechmann condensation reaction of various phenols and β-keto esters.
  • β-amino alcohols by deprotection of epoxides with aromatic amines.
  • Diol derivatives by chemoselective cleavage of acetonides in methanol.

VCl3 can also be used as a reducing agent to determine nitrates and nitrites in water samples.

Analysis Note

Assay (complexometric): ≥ 99.0 %
Identity (ICP-OES): passes test

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302 - H314

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Supplementary Hazards

EUH014

Storage Class Code

8B - Non-combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Vanadium (III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones
Sabitha G, et al.
Tetrahedron Letters, 44(34), 6497-6499 (2003)
Vanadium (III) chloride-catalyzed preparation of β-amino alcohols from epoxides
Sabitha G, et al.
Synthesis, 2003(15), 2298-2300 (2003)
Vanadium (III) chloride: A mild and efficient catalyst for the chemoselective deprotection of acetonides
Sabitha G, et al.
J. Mol. Catal. A: Chem., 238(1-2), 229-232 (2005)
Vanadium (III) chloride as an effective catalyst for the Pechmann reaction
Kumar BS, et al.
Chemistry of Heterocyclic Compounds, 42(2), 172-175 (2006)
Determination of nitrate plus nitrite in small volume marine water samples using vanadium (III) chloride as a reduction agent
Schnetger B and Lehners C
Marine Chemistry, 160, 91-98 (2014)

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