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Key Documents

L050150

Sigma-Aldrich

Cap B2

configured for (ÄKTA® and OligoPilot®)

Synonym(s):

Cap B

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.21

type

for DNA synthesis

Quality Level

product line

Proligo Reagents

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)

color

clear

suitability

conforms to structure (GC, Formulation)

compatibility

configured for (ÄKTA® and OligoPilot®)

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General description

Cap B solution, containing tetrahydrofuran (THF), pyridine and N-methylimidazole (NMI), is mixed in situ with Cap A solution during the capping (acetylation) reaction. Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.Tetrahydrofurane has been replaced by acetonitrile in ÄKTA Cap B1 and B2.Cap B is configured for ÄKTA formulation.

Preparation Note

Acetonitrile / Pyridine 4/6 (v/v)

Other Notes

Cap B2 solution, containing acetonitrile (ACN) and pyridine, is mixed in situ with Cap A and Cap B1 solution during the capping (acetylation) reaction.
Pyridine is applied as a mild base while NMI provides a powerful acylation catalyst.

Legal Information

OligoPilot is a registered trademark of Cytiva
ÄKTA is a registered trademark of Cytiva

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

62.6 °F

Flash Point(C)

17 °C


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