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Anti-AFP antibody produced in rabbit

Name: Anti-AFP antibody produced in rabbit
Brand: SIGMA
Price: 626 CAD

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Alpha-fetoprotein, Anti-FETA, Anti-HPAFP

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Size/SKU	Availability	Price
100 μg	Please contact Customer Service for Availability	$626.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$626.00

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse, rat

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_001125

UniProt accession no.

P02771

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... AFP(174)

Description

General description

The gene AFP (α fetoprotein) encodes a plasma glycoprotein that has a molar mass of 70kDa. The gene is mapped to human chromosome 4. The gene is evolutionarily-related to serum albumin, which is also mapped to human chromosome 4. It is synthesized along with serum albumin during the development of embryonic yolk sac and the liver.

Immunogen

AFP antibody was raised against a 14 amino acid peptide near the amino terminus of human AFP.

Application

Anti-AFP antibody produced in rabbit has been used in immunoflorescence.

Biochem/physiol Actions

α-fetoprotein encoded by the gene AFP is involved in the regulation of fatty acids in both fetal and proliferating adult liver cells. Its expression is found to be increased in acute liver injuries, indicating active liver regeneration. It has been associated with fatty liver disease (FLD), a disease that may lead to cirrhosis and hepatocellular carcinoma. It serves as a tumor marker for HCC (hepatocellular carcinoma).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500533.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA010607	SAB5700032	HPA015642
Sigma-Aldrich SAB3500533 Anti-AFP antibody produced in rabbit	Sigma-Aldrich HPA010607 Anti-AFP antibody produced in rabbit	Sigma-Aldrich SAB5700032 Anti-AFP antibody produced in rabbit	Sigma-Aldrich HPA015642 Anti-AFAP1 antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
species reactivity human, mouse, rat	species reactivity human	species reactivity rat, human, mouse	species reactivity human
UniProt accession no. P02771	UniProt accession no. P02771	UniProt accession no. P02771	UniProt accession no. Q8N556

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c