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SAB3500496

Anti-SIRT5 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-NAD-dependent deacetylase sirtuin-5, Anti-SIR2L5, Anti-Sirtuin 5

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Size/SKUAvailabilityPrice
100 μg
Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)
$580.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), WB
Citations:
2

$580.00


Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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biological source

chicken

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse

technique(s)

indirect ELISA: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SIRT5(23408)

General description

SIRT5 (Sirtuin 5) is a mitochondrial matrix protein belonging to the class III of the sirtuin family. It is localized inside the mitochondria and within the cytosol and nucleus. The protein is widely expressed in the brain, heart, liver and kidney. It is composed of very short amino and carboxyl terminal sequences flanking region with the conserved, catalytic sirtuin center domain.

Immunogen

SIRT5 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SIRT5.

Application

Anti-SIRT5 antibody produced in chicken is suitable for western blot and indirect ELISA.

Biochem/physiol Actions

SIRT5 (Sirtuin 5) is associated with metabolism and aging process. It has been reported in a study that SIRT5 influences urea cycle pathway by NAD-dependent deacetylation and subsequent activation of carbamoyl phosphate synthetase 1 (CPS1), which plays a vital role in the initial step of urea cycle for the detoxification and removal of ammonia. In non-small cell-lung cancer cells. SIRT5 contributions have also been observed for the cancer cell growth and drug resistance. Study shows that SIRT5 may possess oncogenic property.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500496.

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antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

biological source

chicken

biological source

chicken

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

technique(s)

western blot: suitable, indirect ELISA: suitable

technique(s)

indirect ELISA: suitable, western blot: suitable

technique(s)

ChIP: 1—10 μg (per reaction), immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:500-1:1000

technique(s)

immunohistochemistry: 1:200-1:500, immunofluorescence: 0.25-2 μg/mL, immunoblotting: 0.04-0.4 μg/mL

Gene Information

human ... SIRT5(23408)

Gene Information

human ... SIRT6(51548)

Gene Information

human ... SIRT2(22933)

Gene Information

human ... SIRT5(23408)


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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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