Key Documents

Anti-PDL-2 antibody produced in rabbit

Name: Anti-PDL-2 antibody produced in rabbit
Brand: SIGMA
Price: 619 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

PDL2 Antibody - Anti-PDL-2 antibody produced in rabbit, Pdl2 Antibody, Anti-B7DC, Anti-PD-L2, Anti-Programmed cell death 1 ligand-2, Anti-Programmed death ligand 1

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$619.00

About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$619.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

A recombinant, preservative-free antibody is available for your target. Try ZRB2936

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 30 kDa

species reactivity

human, rat, mouse

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_079515

UniProt accession no.

Q9BQ51

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PDCD1LG2(80380)

Description

General description

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as butyrophilin B7-DC or CD273. It belongs to the immunoglobulin superfamily. The gene encoding PDL-2 is localized on human chromosome 9p24.1.

Immunogen

PDL-2 antibody was raised against a 16 amino acid peptide from near the center of human PDL-2.

Application

Anti-PDL-2 antibody produced in rabbit has been used in immunohistochemistry.

Biochem/physiol Actions

The expression of programmed cell death 1 ligand 2 (PD-L2) or CD antigen 273 (CD273) is up-regulated by interferon-γ (IFNG/IFN-γ) stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with colony-stimulating factor-2 (CSF2) and interleukin-4 (IL-4). PD-L2 is involved in the co-stimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500395.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	MABC969	HPA013411	MABC1120
Sigma-Aldrich SAB3500395 Anti-PDL-2 antibody produced in rabbit	Sigma-Aldrich MABC969 Anti-PD-L2 Antibody, clone 24F.10C12	Sigma-Aldrich HPA013411 Anti-PDCD1LG2 antibody produced in rabbit	Sigma-Aldrich MABC1120 Anti-PD-L2 Antibody, clone 366C.9E5
description affinity isolated antibody, buffered aqueous solution	description clone 24F.10C12, from mouse	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description clone 366C.12.9E5.E10.19.1F8, from mouse
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form affinity isolated antibody	antibody form purified immunoglobulin
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source mouse	biological source rabbit	biological source mouse
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
form buffered aqueous solution	form -	form buffered aqueous glycerol solution	form -
shipped in dry ice	shipped in dry ice	shipped in wet ice	shipped in -

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c