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Anti-CXCR4 antibody produced in rabbit

Name: Anti-CXCR4 antibody produced in rabbit
Brand: SIGMA
Price: 584 USD
Availability: InStock

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

Anti-CXCR4

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$584.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD01092337

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), FACS, ICC, IF, IP, WB

Citations:

$584.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

A recombinant, preservative-free antibody is available for your target. Try ZRB1357

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

NP_003458

UniProt accession no.

P61073

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CXCR4(7852)

Description

General description

C-X-C motif chemokine receptor 4 (CXCR4) is encoded by the gene mapped to human chromosome 2q22.1. The gene codes for a protein with seven transmembrane regions. The encoded protein is expressed on the surface of T-cells, B-cells, monocytes, neutrophils and dendritic cells.

Immunogen

CXCR4 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human CXCR4.

Application

Anti-CXCR4 antibody produced in rabbit has been used in western blot analysis and indirect ELISA.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

C-X-C motif chemokine receptor 4 (CXCR4) is specific for stromal cell-derived factor-1. It plays a vital role in regulation of immune response in various immune cell types. CXCR4 interacts with CD4 (cluster of differentiation 4) and permits human immunodeficiency virus type 1 (HIV-1) entry and infection in to the cells. Polymorphism in the gene is associated with the development of Juvenile idiopathic arthritis (JIA). In addition, mutation in the gene increases the risk of susceptibility to cardiovascular diseases (CVDs).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500383.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	SAB3501175	SAB3501176	HPA031999
$Anti-CXCR4 antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich SAB3500383 Anti-CXCR4 antibody produced in rabbit	Sigma-Aldrich SAB3501175 Anti-CXCR4 antibody produced in rabbit	Sigma-Aldrich SAB3501176 Anti-CXCR4 antibody produced in rabbit	Sigma-Aldrich HPA031999 Anti-CXCR2 antibody produced in rabbit
description IgG fraction of antiserum, buffered aqueous solution	description affinity isolated antibody	description affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
antibody form IgG fraction of antiserum	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
species reactivity mouse, human	species reactivity human, rat, mouse	species reactivity rat, human, mouse	species reactivity human

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Storage Class

12 - Non Combustible Liquids

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WGK 1

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