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Anti-IRAK-M antibody produced in rabbit

Name: Anti-IRAK-M antibody produced in rabbit
Brand: SIGMA
Price: 584 USD
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-ASRT5, Anti-IRAKM

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Size/SKU	Availability	Price
100 μg	Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)	$584.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03096977

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

$584.00

Usually ships in 5 business days. (Orders outside of US, please allow an additional 1-2 weeks for delivery)

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

predicted mol wt 66 kDa

species reactivity

rat, mouse, human

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

AF113136

UniProt accession no.

Q9Y616

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... IRAK3(11213)

Description

General description

The IRAKM (interleukin-1 receptor-associated kinase-3) gene is mapped to human chromosome 12q14.3. This gene is predominantly expressed in monocytes and macrophages.

Immunogen

IRAK-M antibody was raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M .

Application

Anti-IRAK-M antibody produced in rabbit has been used in Western blotting, immunoprecipitation and immunofluorescence.

Biochem/physiol Actions

The Irakm (interleukin-1 receptor-associated kinase-3) protein downregulates the toll like receptor (TLR)-signalling and influences the action of nuclear factor-κB (NF-κB). Increased IRAKM expression is observed in inflammatory bowel disease (IBD) and colorectal cancer. It is known to reduce the immune response against microorganism.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500193.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Show Differences

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This Item	SAB1403987	WH0003654M1	WH0051135M5
Sigma-Aldrich SAB3500193 Anti-IRAK-M antibody produced in rabbit	Sigma-Aldrich SAB1403987 Monoclonal Anti-IRAK2 antibody produced in mouse	Sigma-Aldrich WH0003654M1 Monoclonal Anti-IRAK1 antibody produced in mouse	Sigma-Aldrich WH0051135M5 Monoclonal Anti-IRAK4 antibody produced in mouse
description affinity isolated antibody, buffered aqueous solution	description clone 3G6, purified immunoglobulin, buffered aqueous solution	description clone 3F7, purified immunoglobulin, buffered aqueous solution	description clone 1D4, purified immunoglobulin, buffered aqueous solution
biological source rabbit	biological source mouse	biological source mouse	biological source mouse
antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin	antibody form purified immunoglobulin
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in dry ice
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

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12 - Non Combustible Liquids

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