Antioxidant Supplement (1000×) is a proprietary medium supplement. The specific antioxidants and their concentrations are not disclosed.
A1345
Antioxidant Supplement (1000×)
liquid, sterile-filtered, suitable for cell culture
Antioxidant Supplement (1000×)
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Synonym(s):
Antioxidant Solution
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Product Name
Antioxidant Supplement (1000×), liquid, sterile-filtered, suitable for cell culture
sterility
sterile-filtered
form
liquid
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
shipped in
ambient
storage temp.
2-8°C
Quality Level
1 of 4
This Item | P8483 | N6530 | S4920 |
|---|---|---|---|
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| form liquid | form liquid | form solution | form liquid |
| sterility sterile-filtered | sterility sterile-filtered | sterility sterile-filtered | sterility sterile-filtered |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| shipped in ambient | shipped in ambient | shipped in - | shipped in ambient |
| impurities endotoxin, tested | impurities endotoxin, tested | impurities endotoxin, tested | impurities endotoxin, tested |
Application
Antioxidant Supplement (1000×) has been used:
- as a component of the extender media for dilution of sperm samples during cryopreservation[1]
- for long term culture of human-induced pluripotent stem (iPS) cells[2]
- as a component of the immortalization media used for culturing, cloning and expansion of clones for making immortalized cell lines from embryonic mouse kidney[3]
General description
Antioxidant Supplement (1000×) is a proprietary medium supplement specially formulated to boost cell growth for enhanced viral and protein expression. It may be used in combination with Polyamine Supplement (P 8483).
One mL supplements 1 liter of medium.
One mL supplements 1 liter of medium.
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Lan Luo et al.
Scientific reports, 4, 3779-3779 (2014-01-22)
Effects of antioxidants on the quality and genomic stability of induced pluripotent stem (iPS) cells were investigated with two human iPS cell lines (201B7 and 253G1). Cells used in this study were expanded from a single colony of each cell
E Cabrita et al.
Animal reproduction science, 125(1-4), 189-195 (2011-04-13)
During cryopreservation, dilution in the extender media reduces the seminal plasma constituents being cells more vulnerable to oxidative stress. Vitamins (C and E) and the amino acids taurine and hypotaurine are powerful antioxidants naturally present in seminal plasma. Whether their
Tullia Maraldi et al.
Rejuvenation research, 23(2), 93-106 (2019-08-02)
The efficient use of stem cells for transplantation is often limited by the relatively low number of stem cells collected. The ex vivo expansion of human stem cells for clinical use is a potentially valuable approach to increase stem cell
Michael R Duggan et al.
Cell death discovery, 7(1), 60-60 (2021-03-28)
Despite increasing numbers of aged individuals living with HIV, the mechanisms underlying HIV-associated neurological disorders (HANDs) remain elusive. As HIV-1 pathogenesis and aging are characterized by oxidative stress as well as altered protein quality control (PQC), reactive oxygen species (ROS)
Kendall Mitchell et al.
BMC neuroscience, 17(1), 80-80 (2016-12-03)
Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post-operative pain in patients treated with BMP-2 has
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What Antioxidant are present in the supplement and at what concentration?
1 answer-
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Please let me know the ingredients and their concentrations of the product.
1 answer-
The formulation of this product is considered proprietary.
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Does the antioxidant supplement A1345 contain components of animal/human origin?
1 answer-
Product A1345 is free of animal components. This is a specification that is presented on the Certificate of Analysis.
To download a Certificate, or to see a sample Certificate, please navigate to the link below:
https://www.sigmaaldrich.com/product/sigma/a1345#product-documentationHelpful?
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