PZ0312
(S)-PFI-2
Synonym(s):
(S)-8-Fluoro-N-(1-oxo-1-(pyrrolidin-1-yl)-3-(3-(trifluoromethyl)phenyl)propan-2-yl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide hydrochloride, (S)-PFI-2 hydrochloride, PF-06477717 hydrochloride
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About This Item
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assay
≥98% (HPLC)
Quality Level
form
powder
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[H]Cl.O=C(N1CCCC1)[C@H](CC2=CC=CC(C(F)(F)F)=C2)NS(C3=CC4=C(C(F)=C3)CNCC4)(=O)=O
InChI
1S/C23H25F4N3O3S.ClH/c24-20-13-18(12-16-6-7-28-14-19(16)20)34(32,33)29-21(22(31)30-8-1-2-9-30)11-15-4-3-5-17(10-15)23(25,26)27;/h3-5,10,12-13,21,28-29H,1-2,6-9,11,14H2;1H/t21-;/m0./s1
InChI key
ZADKZNVAJGEFLC-BOXHHOBZSA-N
General description
Biochem/physiol Actions
For characterization details of (R)-PFI-2 and (S)-PFI-2, please visit the PFI-2 probe summary on the Structural Genomics Consortium (SGC) website.
(R)-PFI-2, the active SETD7 probe, is available from Sigma. To learn more about and purchase (R)-PFI-2, click here.
To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
Features and Benefits
related product
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| PZ0312-5MG | 04061832632629 |
| PZ0312-25MG | 04061832632612 |
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