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ANTI-FAT1 antibody produced in rabbit

Name: ANTI-FAT1 antibody produced in rabbit
Brand: SIGMA
Price: 607 USD
Availability: InStock

Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-Cadherin-related tumor suppressor homolog precursor, Anti-FAT, Anti-Protein fat homolog

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Size/SKU	Availability	Price
100 μL	Estimated to ship onSeptember 07, 2026fromSAINT LOUIS	$607.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164626

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC

Citations:

$607.00

Estimated to ship onSeptember 07, 2026Details

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Properties

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous solution

species reactivity

human

technique(s)

immunohistochemistry: 1:500- 1:1000

UniProt accession no.

Q14517

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... FAT1(2195)

Description

Immunogen

Cadherin-related tumor suppressor homolog precursor recombinant protein epitope signature tag (PrEST)

Application

Anti-FAT antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project . Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using protein array and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.
The antibody has been used for sandwich ELISA to determine levels of soluble Fat1 in pancreatic cancer serum samples.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

FAT1 (FAT atypical cadherin 1), transmembrane protein belonging to the cadherin super family, encodes a large transmembrane protein with 34 tandem cadherin repeats, five EGF (epidermal growth factor)-like repeats, and a laminin A-G domain. It exhibits tumor suppressor activity. It is ubiquitously expressed in epithelial tissues. Specifically, FAT1 is localized to the cell membrane, often concentrated at filopodia, lamellipodia, and sites of cell-cell contact. In mammals, four isoforms have been found: FAT1, FAT2, FAT3 and FAT4. FAT1 helps to regulate cell-cell association and actin dynamics.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Other Notes

Corresponding Antigen APREST85144

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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This Item	HPA063236	HPA039650	HPA039191
Sigma-Aldrich HPA001869 ANTI-FAT1 antibody produced in rabbit	Sigma-Aldrich HPA063236 Anti-FANCA antibody produced in rabbit	Sigma-Aldrich HPA039650 Anti-VPS51 antibody produced in rabbit	Sigma-Aldrich HPA039191 Anti-LATS2 antibody produced in rabbit
description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution	description Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies
species reactivity human	species reactivity human	species reactivity human	species reactivity human

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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