ALD00604
(+)-PSI Reagent
95%
Synonym(s):
(+)-Ψ, (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide, Phosphorus-Sulfur Incorporation Reagent
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| Size/SKU | Availability | Price |
|---|---|---|
500 mg | Please contact Customer Service for Availability | $288.00 |
5 g | Please contact Customer Service for Availability | $669.00 |
25 g | Please contact Customer Service for Availability | $2,290.00 |
100 g | Please contact Customer Service for Availability | $6,800.00 |
About This Item
Empirical Formula (Hill Notation):
C16H16F5OPS3
CAS Number:
Molecular Weight:
446.46
MDL number:
UNSPSC Code:
12352101
NACRES:
NA.22
Assay:
95%
Form:
powder or crystals
assay
95%
form
powder or crystals
mp
102-107 °C
SMILES string
Fc1c(c(c(c(c1F)F)S[P]2(=S)S[C@]3([C@H](O2)C[C@H](CC3)C(=C)C)C)F)F
InChI key
YPYCUYPOHPPYAS-DWBMIXFYSA-N
Application
Air- and moisture-tolerant, this (+)-PSI Reagent was developed in the Baran lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat# ALD00602).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
Learn more about PI and PSI reagents
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
Learn more about PI and PSI reagents
Legal Information
PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692
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This Item | |||
|---|---|---|---|
| assay 95% | assay 95% | assay ≥95% | assay ≥95% |
| form powder or crystals | form powder or crystals | form crystals | form powder |
| mp 102-107 °C | mp 103-107 °C | mp 119-124 °C | mp 118-123 °C |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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